| 林兰,李鸣镝,刘喜明,王兆礼,楚晓燕,张润云.中药甲亢宁治疗阴虚阳亢型甲状腺功能亢进症的临床研究[J].中国中西医结合杂志,1999,(3):144-147 |
| 中药甲亢宁治疗阴虚阳亢型甲状腺功能亢进症的临床研究 |
| Clinical Study on Hyperthyroidism of Yang Hyperactivity Type due to Yin Deficiency Treated by Jiakang Ning Capsule |
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| DOI： |
| 中文关键词: 甲状腺功能亢进症 甲亢宁 甲状腺功能 心钠素 |
| 英文关键词:hyperthyroidism Jiakang Ning capsule thyroid function atrial natriuretic peptide |
| 基金项目:国家中医药管理局及中国中医研究院资助 |
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| 中文摘要: |
| 目的：观察甲亢宁治疗甲状腺功能亢进症（甲亢）的临床疗效。方法：８５例甲亢患者随机分为甲亢宁组（２４例）、甲亢宁加小剂量他巴唑组（３５例）和他巴唑组（２６例）。观察结束后进行总疗效、主要症状、体重、心电图、甲状腺激素及心钠素（ＡＮＰ）水平的评估。结果：甲亢宁、甲亢宁加小剂量他巴唑组的总有效率（８３３％、９７１％）与他巴唑组（８８５％）比较，无显著性意义（Ｐ＞００５）；在改善甲亢症状方面，甲亢宁组、甲亢宁加小剂量他巴唑组优于他巴唑组（Ｐ＜００５）；３组在改善甲状腺功能和异常心电图、降低血浆ＡＮＰ、增加体重等方面结果相似（Ｐ＞００５）。结论：甲亢宁治疗甲亢疗效满意，中西药联合应用可使疗效有所提高，且未见明显毒副作用。 |
| 英文摘要: |
| Objective: To investigate the effect of Jiakang Ning (JKN) capsule on hyperthyroidism. Methods: Eighty five cases of hyperthyroidism were divided into JKN group (24 cases), JKN with low dose Tapazol group (35 cases) and Tapazol control group (26 cases) at random. The effects were evaluated by total effective rate, using principal symptoms, body weight, EKG, thyroid hormone and atrial natriuretic peptide (ANP) after 6 months. Results: The total effective rates of three groups were 83.8%, 97.1%, 88.5% respectively, and there were insignificant difference among them statistically (P>0 05). The first two groups had better effect in principal symptoms than Tapazol control group (P<0 05). There were similar results in adjusting thyroid dysfunction and abnormal EKG, decreasing ANP and increasing body weight among those three groups (P>0 05). Conclusion: The effect on hyperthyroidism treatment by JKN capsule was satisfactory. The combination of Chinese herbs with western medicine could enhance the curative effect of hyperthyroidism without obvious side effects. |
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