人参注射液治疗充血性心力衰竭及对甲状腺激素的影响

作者	单位
戴小华	安徽中医学院第一附属医院心内科
周宜轩	安徽中医学院第一附属医院心内科
俞兴群	安徽中医学院第一附属医院心内科
韩明向	安徽中医学院第一附属医院心内科

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中文摘要:

目的：观察人参注射液治疗充血性心力衰竭（ＣＨＦ）的疗效及对甲状腺激素的影响。方法：将５４例患者分为两组，对照组以西医常规治疗，治疗组在西医常规治疗的基础上加用人参注射液治疗，疗程均２周，治疗前后采用放射免疫法检测三碘甲状腺原氨酸（Ｔ３）、甲状腺素（Ｔ４）、反三碘甲状腺原氨酸（ｒＴ３）及促甲状腺素（ＴＳＨ）。结果：治疗组总有效率显著优于对照组，平均疗程显著低于对照组；经２周治疗后，治疗组和对照组的Ｔ３、Ｔ４由治疗前较低水平显著升高，ｒＴ３由治疗前的较高水平显著降低（Ｐ＜００５，Ｐ＜００１），而治疗组治疗后这３项指标与对照组比较有显著性差异（Ｐ＜００５，Ｐ＜００１）。结论：人参注射液治疗ＣＨＦ，不仅可提高疗效、缩短疗程，而且可显著纠正ＣＨＦ患者异常的甲状腺激素。

英文摘要:

Objective: To observe the effect of Ginseng injection on congestive heart failure (CHF) and its influence on thyroid hormones. Methods: Fifty four Patients of CHF were divided into two groups. On the basis of conventional treatment of western medicine, the Ginseng injection was given to the treated group additionally. Blood level of triiodothyronine (T 3), thyroxine (T 4), reverse triiodothyronine (rT 3) and thyroid stimulating hormone (TSH) of all patients were determined before and after treatment by radioimmunoassay. Results: There were significant difference between the treated group and the control group in cure rate and mean course of therapy. The levels of T 3 and T 4 of all patients were lower than those of the normal control before treatment, and rT 3 were higher. Two weeks after treatment, T 3 and T 4 level in all patients increased significantly and rT 3 level significantly decreased(P<0 05,P<0 01). Conclusion: Ginseng injection has a good effect on patients with CHF. It also has regulatory effect on thyroid hormones.

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