分期辨证为主治疗糖尿病足及其对下肢动脉超声多普勒血流动力学变化的影响

Staging Syndrome Differentiation in Treating Diabetic Foot Disorder and Its Effect on Hemodynamic Changes of Lower Extremities with Arterial Ultrasonic Doppler Diagnostic Apparatus

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中文关键词: 糖尿病足中医药疗法血管病变药物作用超声多普勒

英文关键词:diabetic foot disorder traditional Chinese medicine vascular lesion drug action ultrasonic Doppler

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作者	单位
范冠杰	Fan Guanjie, Lu Renhe Guangzhou University of TCM, Guangzhou (510405
吕仁和	Fan Guanjie, Lu Renhe Guangzhou University of TCM, Guangzhou (510405

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中文摘要:

目的 :观察分期辨证治疗对糖尿病足的疗效以及对下肢动脉血流动力学变化的影响。方法 :用美国产ATL ULTRAMARK 9HDI型电脑彩色超声诊断仪 ,同时采用中医分期辨证和西药 65 4 2治疗 ,并与无糖尿病足者 (简称对照组 )对照观察 60例 2型糖尿病足患者 (治疗组 30例 ,西药组 30例 )的下肢动脉血流动力学变化及临床疗效。结果 :与对照组比较 ,糖尿病足患者可见下肢动脉的血管内径变小 ,血流量减少 ,血流最大速度、最小速度、平均速度均加快 ,且以足背动脉的变化最为敏感 ;治疗前后比较 ,两组均可以改善下肢动脉的血流动力学 ,以足背动脉的改善为著 ;中医分期辨证治疗的方法使下肢动脉血流动力学改变的效果优于以 65 4 2治疗为主的西药组。综合疗效评定 ,治疗组亦优于西药组 (P <0 0 5 )。结论 :以分期辨证治疗为主的综合疗法治疗糖尿病足效果优于以 65 4 2为主的综合疗法

英文摘要:

To observe the therapeutic effect of staging Syndrome Differentiation of TCM in treating the diabetic foot disorder and the corresponding hemodynamic changes in lower extremities. Methods: Chromatic ultrasonic Doppler diagnostic apparatus (ATL ULTRAMARK 9 HDI, made in USA) was used to determine the arterial hemodynamic changes and clinical effect on the treatment of diabetic foot disorder in 60 non insulin dependent diabetes mellitus (NIDDM) patients, among them 30 were treated by staging Syndrome Differentiation of TCM, and the other 30 as confrol group treated with 654 2, and the 30 cases of nondiabetic foot disoder as normal control group in comparison. Results: Compared to the normal control, the intravascular diameter, blood flow of both freated groups reduced, maximal and minimal speed of blood flow, and the mean speed were accelerated. Values in dorsal pedis artery had present the most sensitive one. In the comparison between before and after treatment, both treated groups were hemodynamic improvement in the lower extremities′ artery, more obviously the dorsal pedis artery, while the comparison between these two groups showed that TCM staging Syndrome Differentiation had a superior effect on lower extremities′ hemodynamics to that of 654 2 group. The comprehensive assessment revealed that the treated groups was also significant different in comparing to that of normal control group (P<0 05). Conclusion: The comprehensive TCM treatment of staging Syndrome Differentiation as the main therapeutic component was prominently better than that of 654 2 application in the treatment.

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