夏连抑幽胶囊治疗幽门螺杆菌感染性胃炎的临床及实验研究

作者	单位
冀爱英	Ji Aiying, Zhao Wenxia, Wang Zhihui, et al The First Affiliated Hospital of Henan College of TCM, Zhengzhou (450000
赵文霞	Ji Aiying, Zhao Wenxia, Wang Zhihui, et al The First Affiliated Hospital of Henan College of TCM, Zhengzhou (450000
王智慧	Ji Aiying, Zhao Wenxia, Wang Zhihui, et al The First Affiliated Hospital of Henan College of TCM, Zhengzhou (450000
杨国红	Ji Aiying, Zhao Wenxia, Wang Zhihui, et al The First Affiliated Hospital of Henan College of TCM, Zhengzhou (450000
陈天朝	Ji Aiying, Zhao Wenxia, Wang Zhihui, et al The First Affiliated Hospital of Henan College of TCM, Zhengzhou (450000
贾士奇	Ji Aiying, Zhao Wenxia, Wang Zhihui, et al The First Affiliated Hospital of Henan College of TCM, Zhengzhou (450000
张玉洁	Ji Aiying, Zhao Wenxia, Wang Zhihui, et al The First Affiliated Hospital of Henan College of TCM, Zhengzhou (450000

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中文摘要:

目的 :观察夏连抑幽胶囊治疗幽门螺杆菌 (HP)感染性胃炎的疗效 ,系统地开发研究“经方”。方法 :将HP感染性胃炎患者随机分为两组 ,治疗组 136例 ,用夏连抑幽胶囊治疗 ,对照组 90例 ,用丽珠得乐胶囊治疗 ,均治疗 4周 ,观察临床疗效 ,并作相应的动物实验。结果 :临床结果显示夏连抑幽胶囊在改善临床症状 ,消除粘膜炎症 ,清除HP方面均较对照组为优 (P <0 0 5 ,P <0 0 1)。动物实验结果表明 ,夏连抑幽胶囊对抗炎、镇痛、胃溃疡模型的影响均有显著作用 ,与对照组比较有显著性差异 (P <0 0 5 ,P <0 0 1)。结论 :夏连抑幽胶囊治疗幽门螺杆菌感染性胃炎疗效肯定。

英文摘要:

Objective: To observe the therapeutic effect of Xialian Yiyou Capsule (XLYYC) on helicobacter pylori (HP) infected gastritis to develop the serial Chinese classical recipe. Methods: HP infected patients were divided into two groups, 136 patients in the XLYYC group treated with XLYYC and 90 patients in the control group treated with Lizhu Dele Capsule, for 4 weeks as one therapeutic course, the clinical therapeutic effect was observed, and corresponding animal experiments were done. Results: Clinical effect of the XLYYC group was better than that of the control group in improving clinical symptoms, relieving inflammation of gastric mucosa and eliminating HP (P<0 05, P<0 01). Results of animal experiment showed that XLYYC was superior than the control significantly in anti inflammation, analgesia, stomach emptying and curing gastric ulcer model (P<0 05, P<0 01). Without any adverse reaction has been found in acute toxicologic study. Conclusion: The therapeutic effect of XLYYC in treating HP infected gastritis was definite and safe, non toxic.

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