张培彤,朴炳奎,孙桂芝,林红生,裴迎霞.肺瘤平二号对中晚期肺癌患者血小板表面糖蛋白表达的影响[J].中国中西医结合杂志,2000,(1):31-33 |
肺瘤平二号对中晚期肺癌患者血小板表面糖蛋白表达的影响 |
Influence of Feiliuping No. 2 on Platelet Surface Glycoprotein Expression in Mid-Late Stage Lung Cancer Patients |
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DOI: |
中文关键词: 中晚期肺癌 活化血小板 血小板 糖蛋白 中药复方 |
英文关键词:mid late stage lung cancer activating platelet platelet glycoprotein Chinese herbal complex recipe |
基金项目:国家中医药管理局青年基金! (No .93C0 1 1 ) |
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中文摘要: |
目的 :观察具有益气养阴、活血解毒作用的肺瘤平二号对中晚期肺癌患者血小板表面糖蛋白表达和血小板激活状态的影响。方法 :采用流式细胞技术检测 30例中晚期肺癌患者服肺瘤平二号前后血小板表面糖蛋白CD4 1/CD4 2a、CD36 /TSP、CD6 2 /CD6 3、CD9、CD31表达的改变 ,并与 50名健康志愿者的检测结果进行对照。结果 :中晚期肺癌患者血小板表面糖蛋白的表达及血小板激活状态明显高于健康志愿者。结论 :服肺瘤平二号可以部分减少中晚期肺癌患者血小板表面糖蛋白的表达和血小板激活状态。 |
英文摘要: |
Objective: To explore the influence of Feiliuping NO. 2 (FLP), a Chinese herbal preparation for reinforcing Qi, nourishing Yin, activating blood circulation and detoxifying, on surface glycoprotein expression (SGPE) and activated condition of platelet in mid late stage lung cancer patients. Methods: Changes of platelet surface expression of CD41/CD42a, CD36/TSP, CD62/CD63, CD9 and CD31 were measured before and after FLP treatment by using flow cytometer in 30 cases of mid late stage lung cancer. Results: The SGPE and activated condition of platelet in mid late stage lung cancer patients were significantly higher than those of healthy person, and both could be reduced partly by FLP. Conclusion: FLP could influence the SGPE and activate condition of platelet in lung cancer patients. |
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