活血益气养阴方防治急性放射损伤的研究

作者	单位
王炳胜	WANG Bingsheng, LIU Xiufang, WANG Tao, et al NO. 251 Hospital, Zhangjiakou, Hebei (O75000
刘秀芳	WANG Bingsheng, LIU Xiufang, WANG Tao, et al NO. 251 Hospital, Zhangjiakou, Hebei (O75000
王涛	WANG Bingsheng, LIU Xiufang, WANG Tao, et al NO. 251 Hospital, Zhangjiakou, Hebei (O75000
付显成	WANG Bingsheng, LIU Xiufang, WANG Tao, et al NO. 251 Hospital, Zhangjiakou, Hebei (O75000
赵增虎	WANG Bingsheng, LIU Xiufang, WANG Tao, et al NO. 251 Hospital, Zhangjiakou, Hebei (O75000
胡世金	WANG Bingsheng, LIU Xiufang, WANG Tao, et al NO. 251 Hospital, Zhangjiakou, Hebei (O75000

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中文摘要:

目的：用活血益气养阴中药减轻放疗急性毒副反应。方法：７２例鼻咽癌患者分成两组，各３６例，均行根治性放疗，放疗中实验组（Ａ组）服用中药活血益气养阴方。对照组（Ｂ组）用维斯克含漱或外敷。结果：口腔粘膜和皮肤损伤Ａ、Ｂ两组各为４７．２％（１７／３６例）９１．７％（３３／３６例），１３．９％（５／３６例）、３３．３％（１２／３６例）；损伤程度各不相同。Ａ、Ｂ两组口腔粘膜损伤时的放射剂量（Ｇｙ）各为４１．４±９．４，３０．９±８．９；皮肤损伤时的放射剂量各为４８．１±５．６，４３．２±６．３。两组比较有显著性差异（Ｐ＜０．０１）。骨髓抑制例数及程度两组比较，有显著性差异（Ｐ＜０．０１）。结论：活血益气养阴方能明显减轻粘膜皮肤的急性放射损伤及骨髓抑制。

英文摘要:

To reduce the acute toxic and side-effect of radiotherapy with Huoxue Yiqi Yangyin recipe (HYYR). Methods: Seventy-two nasopharyngeal carcinoma patients that using radiotherapy were divided into two groups: HYYR group (A) and the control group (B) using Wisk lotion for gargling or apply at the skin lesion. Results: The injury on mucous membrane of mouth cavity and skin were 47.2%, 91.7%, 13.9%, 33.3% in group A and B respectively, the degree of injury was different (P<0.01 ). The acute reaction of the mucous membrane of mouth cavity did not occur until the cumulative radiation were 41.4±9.4, 30.9±8.9 in group A and B respectively, there was significant difference between the two groups (P<0.01). Conclusion: HYYR can reduce the acute radioactive reaction of the skin and mucous membrane of mouth cavity and inhibition of bone marrow.

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