中西医结合治疗轻、中度充血性心力衰竭的临床研究

目的：观察中药联合卡托普利和倍他乐克治疗轻、中度充血性心力衰竭的疗效。方法：将150例患者随机分为3组，A组单用中药治疗上组单用西药卡托普利加倍他乐克，C组中西药联合应用；3组均在用药后3周和3个月分别观察心功能各项指示。结果：（1）心功能总有效率A组为72％，B组为86％，C组为94％。（2）超声心动图左室舒张末期内径C组较A、B两组明显缩小（P＜0．05）。（3）射血分数C组比A、B两组有显著提高（P＜0．05）。（4）24h动态心电图C组室性早搏数比A、B组显著减少（P＜0．05）。结论：中药联合卡托普利加倍他乐克联合应用提高了轻、中度充血性心力衰竭的疗效。

英文摘要:

To evaluate the effect of combined use of Chinese herbal medicine, Captopril and Metoprolol in treating mild-middle degree congestive heart failure. Methods: One hundred and fifty patients studied were divided into 3 groups, the Group A treated with Chinese herbal medicine, Group B treated with Captopril plus Metoprolol and Group C treated with both Chinese and western medicines. Parameters on cardiac functions were observed and compared 3 waks and 3 months after treatment respectively. Result8: (1) The cure rate in the Group A, B and C was 72 %, 86% and 94 % respectively. (2) Effect of echocardiogram: ultrasound cardiogram showed that the left ventricular diastolic diameter in Group C was less significantly than that in Group A and B (P < 0. 05). (3) The eject fraction in Group C was higher than that in the other two groups (P<0. 05). (4)The 24 hours dynamic electrocardiogram demonstrated a significant lowering occurrence of ventricular premature contraction in Group C in comparing with that in Group A and B (P < O. o5). Conclusion: Good effect would be expected in treating mild-midd1e degree congestive heart failure by using Chinese herbal medicine combined with Captopril and Metoprolol.

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