刘秀芳,王炳胜,付显成,赵增虎,丁瑞亮,李成云.中药配合同步放、化疗对晚期非小细胞肺癌的影响[J].中国中西医结合杂志,2000,(6):427-429 |
中药配合同步放、化疗对晚期非小细胞肺癌的影响 |
Clinical Study on Treatment of Advanced Non-Small Cell Lung Cancer with Chinese Herbal Medicine Combined with Synchronous Radio-and Chemotherapy |
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DOI: |
中文关键词: 肺癌 中药 同步放化疗 综合疗效 |
英文关键词:lung cancer Chinese herbal medicine synchronous radio-and chemotherapy comprehensive therapeutic effect |
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中文摘要: |
目的:探讨中药辨证治疗配合同步放、化疗对晚期非小细胞肺癌(NSCLC)的影响。方法:对56例(A组)晚期NSCLC患者采用中医辨证治疗加同步放、化疗,并与44例同步放、化疗(B组)及34例放、化疗(C组)进行对照,结果:A、B、C组近期有效率分别为87.5%、84.1%、55.9%,A、B两组优于C组(P<0.01);中位生存期A组为16.4个月,B组为11.8个月,C组为10.6个月;2、3年生存率A组明显高于B组(P<0.05),且A组患者临床症状变化、卡氏评分、免疫功能明显改善(P<0.05,P<0.01)。结论:中药配合同步放、化疗对晚期NSCLC患者的免疫功能,生存质量,延长生存时间均优于单纯同步放、化疗及放、化疗。 |
英文摘要: |
Objective: To explore the effect of applying Chinese herbal medicine according to Syndrome Differentiation of TCM combined with synchronous radio- and chemotherapy (combination therapy) in treating advanced non small cell lung cancer (NSCLC). Methods: The 56 patients in the group A were treated with combination ther apy, and the 44 patients in the group B treated with synchronous radio- and chemotherapy, while the 34 pa tients in the group C treated with non-synchronous radio- and chemotherapy. The efficacy of treatment in the three groups were observed and compared. Results: The immediate effective rate in the A, B, C groups was 87.5%, 84. 1% and 55. 9% respectively, that in the group A and B was better than that in the group C (P< 0.01). The median survival time in the three groups was 16. 4, 11. 8 and 10. 6 months respectively. The 2-year and 3-year survival rate in the group A were markedly higher than those in the group B (P<0.05), moreover, the clinical symptoms, Karnovsky scoring and immune function were obviously improved in the group A (P< 0. 05, P<0. 01). Conclusion: Effect of the combination therapy is superior to that of synchronous radio- and chemotherapy alone in improving immune function, elevating quality of life and prolongating survival time of pa tients with NSCLC. |
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