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高新平,赵卫星,张志亮,刘彩莉,李汉臣,杜华贞,杨廷桐.黄芪增免散对围手术期食管癌间质反应的影响[J].中国中西医结合杂志,2001,(3):171-173
黄芪增免散对围手术期食管癌间质反应的影响
Effect of Huangqi Zengmian Powder on Interstitial Response in Patients with Esophageal Cancer at Peri-Operational Period
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DOI:
中文关键词:  黄芪增免散  食管癌  间质反应  肥大细胞  免疫功能
英文关键词:Huangqi Zengmian Powder  esophageal cancer  interstitial response  mastocyte  immune function
基金项目:河南省教委科研基金
作者单位
高新平 新乡医学院病理学教研室 
赵卫星 新乡医学院病理学教研室 
张志亮 新乡医学院第一附属医院 
刘彩莉 新乡医学院第一附属医院 
李汉臣 新乡医学院第一附属医院 
杜华贞 新乡医学院病理学教研室 
杨廷桐 新乡医学院病理学教研室 
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中文摘要:
      目的 :观察黄芪增免散对围手术期食管癌间质反应的影响。方法 :用黄芪增免散治疗围手术期食管癌患者 37例 ,共 4周。采用甲苯胺蓝染色方法 ,对手术切除标本进行组织学观察用药后食管癌间质(包括肥大细胞、微血管和淋巴细胞 )反应的变化 ,并与同期手术治疗的 14例患者作对照。结果 :与对照组比较 ,治疗组食管癌间质肥大细胞数量和淋巴细胞灶状聚集增多 ,间质微血管损伤现象明显 (P <0 0 1)。结论 :黄芪增免散对围手术期食管癌患者免疫功能有改善作用。
英文摘要:
      Objective: To observe the effect of Huangqi Zengmian Powder (HQZMP) on interstitial response of esophageal cancer at peri operational period. Methods: Thirty seven patients of esophageal cancer were treated with HQZMP for 4 weeks peri operationally. The pathological interstitial changes (including mastocyte, microvessels and lymphocytic response) in resected esophageal cancer sample were observed using toluidine blue stain. Results: As compared with the non HQZMP treated control group, quantity of interstitial mastocyte, focal lymphocytic aggregation and interstitial microvessel damage in the HQZMP treated group were more obvious (P<0 01). Conclusion: HQZMP could improve the immune function of esophageal patients in peri operational period.
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