珠黄霜对肛门术后创面羟脯氨酸的影响

作者	单位
郑雪平	江苏省南京市中医院!南京210001
丁义江	江苏省南京市中医院!南京210001
郑妙贞	江苏省南京市中医院!南京210001
潘仁智	江苏省南京市中医院!南京210001
吴金萍	江苏省南京市中医院!南京210001
丁曙晴	江苏省南京市中医院!南京210001
严传强	江苏省南京市中医院!南京210001

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中文摘要:

目的 :观察外用中药珠黄霜对肛门术后创面肉芽组织中羟脯氨酸 (Hyp)含量的影响。方法 :将 50例低位单纯性肛瘘术后患者随机分为珠黄霜治疗组和马应龙麝香痔疮膏阳性药物对照组 ,分别在术后第 3、7、14天创面肉芽组织上取材 ,应用碱水解比色法检测Hyp的含量。结果 :术后第 7、14天创面Hyp含量治疗组显著高于对照组 ,第 3天两者差异无显著性。结论 :珠黄霜能显著提高肛门术后创面肉芽组织中Hyp的含量。

英文摘要:

Objective: To observe the effect of Zhuhuang Frost (ZHF), an external preparation of Chinese herbal medicine, on level of hydroxy proline (Hyp) in surgical wound after anal operation. Methods: Fifty postoperational patients after low position simple operation of anal fistula were randomly divided into two groups and treated with ZHF and Mayinglong Musk hemorrhoidal paste (MMHP) respectively. The level of Hyp in granulation of wound was tested using alkaline hydrolysis assay at the 3rd, 7th and 14th day after operation respectively. Results: The Hyp level tested at the 7th and 14th day after operation in the ZHF treated group was higher than that in the MMHP treated group, but those tested at the 3rd postoperational day in the two groups was not different significantly. Conclusion: ZHF could increase the Hyp level in postoperational granulation of wound after anal operation.

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