中西医结合长疗程治疗强直性脊柱炎的临床观察

作者	单位
曹铁梅	中国人民解放军第二○八医院
韩宏妮	中国人民解放军第二○八医院
段英春	中国人民解放军第二○八医院
陈立忠	中国人民解放军第二○八医院
姬艳波	中国人民解放军第二○八医院
王兵	中国人民解放军第二○八医院
王海燕	中国人民解放军第二○八医院

摘要点击次数: 1321

全文下载次数: 1301

中文摘要:

目的 :研究控制疾病进展、缩短疗程、减少致残的中西医结合治疗强直性脊柱炎的新疗法。方法 :选择确诊的强直性脊柱炎 2 19例做为研究对象 ,追踪观察 2年。治疗组 (A组 )坚持中西医结合治疗10个月以上者 10 6例 ;西药对照组 (B组 ) 48例 ,非甾体抗炎镇痛药对照组 (C组 ) 34例。结果 :(1)近期疗效 :A组显效率为 73 58% (78/ 10 6例 ) ,总有效率为 96 2 3% ;B组显效率为 4 7 92 % (2 3/ 4 8例 ) ,总有效率为87 50 % ;C组显效率为 5 88% (2 / 34例 ) ,总有效率为 4 1 18% ;A组与B组比较差异有显著性 (χ2 =10 58,P <0 0 1) ,A组优于B组 ;A组与C组比较差异有显著性 (χ2 =6 7 76 ,P <0 0 1) ,A组优于C组。 (2 )两年后随访 :A组有效者复发率为 18 37% (9/ 4 9例 ) ,B组有效者复发率为 30 4 3% (7/ 2 3例 ) ,A组与B组比较差异无显著性 (χ2 =1 32 ,P >0 0 5) ,C组有效者复发率为 6 6 6 7% (8/ 12例 ) ,A组与C组比较差异有显著性 (χ2 =11 19,P <0 0 1) ,C组复发率高于A组。结论 :中西医结合长疗程治疗强直性脊柱炎集中、西两医优点 ,其方法可行 ,疗效可靠 ,副作用较少 ,具有推广应用价值。

英文摘要:

Objective: To seek for the new method of integrated traditional Chinese and western medical treatment (TCM-WM) for ankylosing spondylitis (AS) to control the disease development, shorten the therapeutic course and reduce disability rate. Methods: Patients of AS enrolled in this study were 106 patients in group A, who were persistently treated with TCM-WM for over 10 months, 48 patients in group B treated with western medicine and 34 in group C treated with non-steroidal anti-inflammatory and analgesic agents. They were followed-up for 2 years. Results: (1)Short-term effect: the markedly effective rate in the three groups was 73.58%, 47.92% and 5.88% respectively, and the total effective rate was 96.23%, 87.50% and 41.18% respectively. The comparisons of group A to group B and C showed significant difference, the effect in group A was superior to that in group B and group C (χ 2=10.58,P<0.01 and χ 2=67.76,P<0.01 respectively). (2)Results of 2-year follow-up: the recurrence rate in group A was 18.37% (9/49), it was insignificantly different from that in group B (7/23=30.43%, χ 2=1.32,P>0.05), but significantly different from that in group C (8/12=66.67%, χ 2=11.19,P<0.01). Conclusion: Long-term TCM-WM therapy, which concentrated on the advantages of traditional Chinese and western medicine, was a practical method in treating AS with reliable effect, few side-reaction, therefore, is worth spreading.

关闭