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章梅,马世平,王宗仁,夏天.芪丹通脉片对2型糖尿病患者血糖和血脂的影响[J].中国中西医结合杂志,2001,(11):825-827
芪丹通脉片对2型糖尿病患者血糖和血脂的影响
Effect of Qidan Tongmai Tablet on Glucose and Lipid Metabolism in Patients with Diabetes Mellitus Type 2
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DOI:
中文关键词:  芪丹通脉片  2型糖尿病 血脂  血糖
英文关键词:Qidan Tongmai tablet  diabetes mellitus  blood lipid  blood glucose
基金项目:
作者单位
章梅 西安交通大学第一医院中医科 
马世平 第四军医大学西京医院 西安710033 
王宗仁 第四军医大学西京医院 西安710033 
夏天 第四军医大学西京医院 西安710033 
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中文摘要:
      目的 :研究芪丹通脉片对 2型糖尿病患者血糖和血脂代谢的影响。方法 :12 8例糖尿病患者在原降糖治疗的基础上分为 4组 ,即 :不合并 (A组 )和合并 (B组 )高脂血症各 33例加服芪丹通脉片 ,不合并(C组 )和合并 (D组 )高脂血症各 31例服淀粉制剂为对照组 ,疗程均为 2个月。结果 :A、B两组空腹血糖、餐后 2h血糖和糖化血红蛋白均下降 ,总胆固醇和甘油三酯降低 ,高密度脂蛋白胆固醇升高 ,与治疗前比较差异均有显著性 (P <0 0 1) ;C、D两组治疗前后上述各项指标无明显变化。服用芪丹通脉片患者未见明显副作用。结论 :芪丹通脉片对 2型糖尿病患者除可调节异常血脂外 ,尚有一定降低血糖作用。
英文摘要:
      Objective: To study the effect of Qidan Tongmai tablet (QDTMT) on glucose and lipid metabolism in patients with diabetes mellitus (DM) type 2. Methods: Patients of DM, with or without hyperlipidemia complication (HLC) were divided into 4 groups, Group A (33 cases without HLC) and B (33 cases with HLC) were treated by QDTMT, Group C (31 cases without HLC) and D (31 cases with HLC) were not treated by QDTMT. The treatment was carried out on the previous basic hypoglycemic treatment with a therapeutic course of 2 months. Results: The levels of fasting glucose, 2 hrs postprandial blood glucose and glycosylated hemoglobin, as well as the levels of total cholesterol and triglyceride lowered, and the high density lipoprotein increased in Group A and B after treatment, as compared with those before treatment, the difference was significant (P<0 01). While in Group C and D, the above mentioned indexes were not changed significantly (P>0 05). No apparent side effect was found in the QDTMT treatment period. Conclusion: Besides regulating abnormal blood lipid, QDTMT has also a hypoglycemic effect in certain degree in patients with DM type 2.
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