火把花根片治疗肾病综合征继发脂质代谢紊乱的临床观察

作者	单位
伍新林	中山医科大学附属第一医院中医科广州510080
李俊彪	中山医科大学附属第一医院中医科广州510080
莫穗林	中山医科大学附属第一医院中医科广州510080
周莺	中山医科大学附属第一医院中医科广州510080
沈维增	中山医科大学附属第一医院中医科广州510080

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中文摘要:

目的 :探讨火把花根片对肾病综合征继发脂质代谢紊乱的作用。方法 :96例肾病综合征患者随机分成两组 ,治疗组 6 0例以火把花根片治疗 ,对照组 36例以激素或细胞毒性药物治疗 ,6个月后观察两组的疗效及血脂、肾功能等相关指标的变化情况。结果 :治疗组总有效率为 88 33% ,对照组总有效率为6 9 4 4%。治疗组明显优于对照组 (P <0 0 5 ) ;治疗组在改善血脂代谢及肾功能等方面也明显优于对照组(P <0 0 5 )。结论 :火把花根片能明显改善肾病综合征继发的脂质代谢紊乱 ,可改善肾功能 ,消除蛋白尿 ,升高血浆白蛋白。

英文摘要:

To study the effect of Colquhounia root table t ( CRT) in treating nephrotic syndrome with sequential lipid metabolism disorder (N S LMD). Methods: The 96 patients with NS LMD were randomly divided in to two groups, the 60 cases in the treated group treated with CRT and the 36 cases in the control group treated with hormone or cytotoxic medicine. The curative e ffect and the related indexes were determined before and after treatment. Results: After six months treatment, the general effective rat e in the treated group was 88.33%, which was markedly higher than that in the co ntrol group (69.44%, P<0 05). The levels of the treated group in ameliorating lipid metabolism disorder and renal dysfunction were also higher than those in the control group (P<0 05). Conclusion: CRT could improve NS LMD, improve renal function, eliminate urinary protein and increase plasma albumin. It is highly effective w ith low toxicity and safe.

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