血塞通软胶囊防治产后出血的临床观察

作者	单位
刘冬岩	首都医科大学附属北京妇产医院北京100006
范玲	首都医科大学附属北京妇产医院北京100006
黄醒华	首都医科大学附属北京妇产医院北京100006
王琪	首都医科大学附属北京妇产医院北京100006
王晓梅	首都医科大学附属北京妇产医院北京100006

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中文摘要:

目的 :探讨血塞通软胶囊对产后出血的双向治疗作用。方法 :6 0例产妇随机分为治疗组和对照组 (各 30例 ) ,分别用血塞通软胶囊和安慰剂治疗 7天 ,观察产后出血情况。结果 :两组血红蛋白、红细胞数量、红细胞压积及心脏指数产后第 3天均低于产前 (P <0 0 5或P <0 0 1) ;网织细胞 :治疗组产后低于产前 ,但差异无显著性 ,对照组产后低于产前 (P <0 0 5 )。出血时间 :治疗组产后较产前明显缩短 (P <0 0 5 ) ,对照组产后与产前相比无明显变化。血液粘度 :对照组产前和产后比较差异有显著性 (P <0 0 5 )。产后 30min、1h、2h、2 4h出血量治疗组均明显低于对照组 (P <0 0 5 ,P <0 0 1)。子宫缩复情况 :产后第 2、4、7天治疗组均明显优于对照组 (P <0 0 5 )。结论 :血塞通软胶囊对产后止血确有疗效 ,并可促进子宫复旧 ,减少产后恶露 ,加速产妇产后恢复。

英文摘要:

Objective: To observe the effect of Xuesaitong (XST) soft capsule in treating postpartum hemorrhage. Methods: Sixty pregnant women were randomly divided into the treated group (A) and the control group (B), 30 cases in each, they were treated with XST and placebo respectively for 7 days to observe the changes of hemorrhagic conditions. Results: After delivery, the hemoglobin, RBC count, hematocrit and cardiac index were lower at 3rd day than those before delivery in both groups (P<0 05 or P<0 01), reticulocyte count lowered insignificantly as compared with that before delivery in group A but significantly in control group B; the bleeding time shortened significantly in group A (P<0 05) but unchanged in group B; significant change of blood viscosity only found in group B (P<0 05). The amount of bleeding 30 min, 1hr, 2hrs and 24 hrs after delivery in group A was all lower than that in group B respectively (P<0 01 or P<0 05). Involution of uterus in group A at 2nd, 4th and 7th day after delivery was all better than that in group B respectively (P<0 05). Conclusion: XST has definite effect in decreasing postpartum hemorrhage, it also shows effects in promoting involution of uterus, reducing lochia and accelerating recovery of parturients.

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