| 丁国安,余国汉,陈顺芬,冯容妹,关炳波,梁绍财,黄鹏,陆小兵.益智合剂与利他林联合治疗儿童多动症的疗效评价[J].中国中西医结合杂志,2002,(4):255-257 |
| 益智合剂与利他林联合治疗儿童多动症的疗效评价 |
| Assessment on Effect of Treatment for Childhood Hyperkinetic Syndrome by Combined Therapy of Yizhi Mixture and Ritalin |
| 免费下载全文 查看/发表评论 下载PDF阅读器 |
| |
| DOI： |
| 中文关键词: 儿童多动症 益智合剂 利他林 临床疗效 |
| 英文关键词:childhood hyperkinetic syndrome Yizhi Mixture Ritalin clinical effect |
| 基金项目: |
|
| 摘要点击次数: 1450 |
| 全文下载次数: 1534 |
| 中文摘要: |
| 目的 :探寻一种较好的治疗儿童多动症 (childhoodhyperkineticsyndrome ,CHS)的方法。方法 :2 10例CHS患儿随机分成益智合剂联合利他林治疗组 (综合组 )、益智合剂治疗组 (中药组 )、利他林治疗组 (西药组 )各 70例 ,并进行 12周的对照观察。用多动指数量表 (Conners)、父母症状问卷 (Achenbach)、临床总体印象量表 (CGI)、副反应量表 (Tess)于治疗前后评定。结果 :总有效率综合组 82 8% ,中药组、西药组分别为 75 7%、74 2 % ;显效率综合组 80 0 % ,中药组、西药组分别为 4 4 3%、4 5 7%。经 χ2 检验 ,3组总有效率比较差异无显著性 (P >0 0 5 ) ,3组显效率比较差异有显著性 (χ2 =2 3 31,P <0 0 1) ,进一步运用 χ2 分割法进行 3组间两两比较后 ,综合组与中药组及西药组的显效率比较差异均有显著性 (χ21=18 98,P <0 0 1;χ22 =17 6 2 ,P <0 0 1) ,其中综合组显效率高。 3组多动指数总分、行为总分较治疗前均明显降低 ,语文及数学成绩明显提高 ,3组间两两比较 (采用 q检验 )后发现 ,综合组与中药组、西药组在治疗后的多动指数总分、行为总分、语文及数学成绩方面差异均有显著性 (P <0 0 5 )。综合组及中药组还能显著改善患儿软神经体征及异常脑电图 ,副反应明显低于西药组 (P <0 0 1)。结? |
| 英文摘要: |
| Objective: To seek for a good therapy for childhood hyperkinetic syndrome (CHS). Methods: Two hundred and ten patients of CHS were randomly divided into three groups, the Yizhi mixture (YZM) group, the Ritalin group and the combined treated group, 70 in each group. They were treated with YZM alone, Ritalin alone and combined YZM and Ritalin respectively for 12 weeks. The effect was assessed by Conners′ questionnaire for hyperkinetic scoring, Achenbach′s questionnaire for behavior estimation, clinical general image questionnaire and Tess′s questionnaire before and after treatment. Results: The total effective rate in the YZM group, Ritalin group and combined treated group was 75.7%, 74.2% and 82.8% respectively, and the markedly effective rate in the three groups was 44.3%, 45.7% and 80.0% respectively. By χ 2 test, comparison among the three groups showed that the difference of the total effective rate was insignificant, while that of the markedly effective rate was significant (χ 2=23 31,P<0 01). Further analysis conducted by partitioning method to make comparison between each two groups showed that the markedly effective rate was significantly higher in the combined treated group than that in the YZM group (χ 2=18 98,P<0 01) and in the Ritalin group (χ 2=17 62,P<0 01). The low hyperkinetic score, behavior score, achievement of Chinese and mathematics in the CHS patients were improved after treatment, the improvements were significantly higher in the combined treated group than those in the other two groups (P<0 05, by q test). Moreover, the soft nerve signs and abnormal encephalogram were significantly improved in the combined treated and the YZM groups, and the side effect occurred in the two groups was less than that in the Ritalin group (P<0 01). Conclusion: The therapeutic effect of combined treatment of YZM and Ritalin was better than that of YZM or Ritalin alone. |
| 关闭 |
|
|
|
扫描微信二维码，获取更多信息