中西医结合治疗抗心磷脂抗体阳性反复早期自然流产临床观察

Clinical Observation on Effect of Chinese Herbal Medicine Plus Human Chorionic Gonadotropin and Progesterone in Treating Anticardiolipin Antibody-Positive Early Recurrent Spontaneous Abortion

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DOI：

中文关键词: 反复流产抗心磷脂抗体中药绒毛膜促性腺激素黄体酮

英文关键词:recurrent spontaneous abortion anticardiolipin antibody Chinese herbal medicine human chorionic gonadotropin progesterone

基金项目:

作者	单位
舒静	宁波市第一医院妇产科
缪频	宁波市第一医院妇产科
王若楷	宁波市李惠利医院妇产科

摘要点击次数: 1745

全文下载次数: 1960

中文摘要:

目的 :寻找一种无须用皮质激素、阿斯匹林或肝素的方法治疗抗心磷脂抗体阳性的反复流产。方法 :选择 2 3例抗心磷脂抗体阳性反复流产者为研究组 ,对其采用中药加绒毛膜促性腺激素和黄体酮的方法进行治疗 ;另 18例同样病例为对照组 ,仅采用多种维生素治疗。抗心磷脂抗体采用酶联免疫吸附法测定。结果 :研究组抗心磷脂抗体转阴率为 86 9% (2 0 / 2 3例 ) ,流产治愈率为 82 6 % (19/ 2 3例 ) ,抗体转阴者的流产治愈率为 95 % (19/ 2 0例 ) ;对照组的流产治愈率为 16 7% (3/ 18例 ) ,两组流产治愈率比较差异有显著性 (P <0 0 1)。结论 :用中药加绒毛膜促性腺激素和黄体酮的方法能有效治愈抗心磷脂抗体阳性的反复流产。

英文摘要:

Objective: To find a method without corticosteroids, aspirin or heparin for treatment of anticardiolipin antibody positive early recurrent spontaneous abortion (AARSA). Methods: Twenty three patients of AARSA in the treated group were treated with Chinese herbal medicine (CHM) plus human chorionic gonadotropin and progesterone, and 18 patiens in the control group were treated with multi vitamin only. The change of anticardiolipin antibody was determined by enzyme linked immunoabsorbent assay (ELISA). Results: After treatment, anticardiolipin antibody negative converted in 20 cases (86.9%) of the treated group. The cure rate of abortion in the treated group was 82.6% (19/23), which was raised to 95% (19/20) in those patients with antibody negative conversion, while in the control group, it was 16.7% (3/18) merely, comparison between the two groups in cure rate showed significant difference (P<0 01). Conclusion: CHM plus human chorionic gonadotropin and progesterone could cure AARSA effectively.

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