心脉通胶囊对急性心肌梗死患者存活心肌血流灌注的影响

作者	单位
孟君	中山医科大学附属第一医院
冯君	中山医科大学附属第一医院
贺敬波	广东省深圳市宝安区人民医院
丘瑞香	中山医科大学附属第一医院

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中文摘要:

目的 :探讨心脉通胶囊对急性心肌梗死 (AMI)患者存活心肌的保护作用及机制。方法 :4 6例急性心肌梗死患者随机分为治疗组 (2 3例 ,用常规西药加心脉通胶囊治疗 )与对照组 (2 3例 ,单用常规西药治疗 ) ,通过比较两组治疗前后核素分布异常节段计数、计分及核素心肌显像缺损范围分数和严重程度积分的变化 ,观察心脉通胶囊对心肌缺血区血流灌注的影响。结果 :治疗组患者治疗后的核素分布异常节段计数、计分及核素心肌显像缺损范围分数和严重程度积分下降 ,与对照组比较差异均有显著性 (P <0 0 5 )。结论 :心脉通胶囊具有较好改善冠脉血流量 ,增加心肌缺血区灌注的作用 ,对AMI存活心肌具有保护作用

英文摘要:

Objective: To explore the protective effect and mechanism of Xinmaitong Capsule (XMTC) on the viable myocardium in patients with acute myocardial infarction (AMI). Methods: Forty six patients with AMI were randomly divided into the XMTC group (n=23), treated with conventional treatment combined with XMTC, and the control group (n=23), treated by conventional treatment alone. The effect of XMTC was observed by comparing the changes of nuclide abnormal segments′s count and scoring, as well as scoring of nuclide filling defect between the two groups. Results: Significant differences were found in comparing the changes between the two groups in all the above mentioned parameters (P<0 05). Conclusion: XMTC has good effects in improving coronary blood flow and increasing the myocardial blood perfusion of ischemic area, thus it shows the protective effect on the viable myocardium in patients with AMI.

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