邹金盘,花宝金,陈长怀,徐贵成,苏浩,王寅,李光熙,杨宗艳,何夏秀,刘喜明,倪青,李辉,赵宏,张丽娜,汪卫东.42例SARS患者临床特征与中西医结合治疗[J].中国中西医结合杂志,2003,(7):486-488,491 |
42例SARS患者临床特征与中西医结合治疗 |
Clinical Characteristics and Integrative Chinese and Western Medicine Treatment of 42 Patients of Severe A-cute Respiratory Syndrome (SARS) |
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DOI: |
中文关键词: 严重急性呼吸综合征(SARS) 临床特征 中西医结合治疗 |
英文关键词:severe acute respiratory syndrome clinical characteristics integrative Chinese and western medical treatment |
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中文摘要: |
目的:了解SARS的临床特征,探索中西医结合治疗的有效方法。方法:对确诊的SARS患者病历资料进行总结与分析,并进行中西医结合治疗观察。结果:42例患者早期发热100%,头痛92.9%,畏寒76.2%,胸闷76.2%,咳嗽73.8%,肌肉酸痛88.1%;肺损伤累及≥3叶者42.9%,累及2叶者47.6%,累及1叶者9.5%;肝功能升高(ALT或AST)61.9%;心肌酶(CK或CK-MB)升高47.6%;T淋巴细胞亚群中CD3+低于正常91.1%(31/34例),CD4+/CD8+比值偏低76.5%(26/34例)。中晚期患者神疲乏力85.7%,恐惧感81.0%,气短或胸闷71.4%,食欲不振64.3%,舌质淡暗52.4%,舌苔黄白相兼45.2%,舌苔中根部黄厚21.4%。治愈出院时多无明显临床症状,胸片肺部病灶92.8%完全吸收,CD3+复查30例,仍有70%患者低于正常,CD4+/CD8+比值偏低36.7%。经中西医结合治疗(早期只用西药,中晚期中西药合用)后全部治愈出院,无1例 亡病例。发热消退时间平均(3.52±0.85)天,胸部X片肺部病灶完全吸收平均时间(26.82±5.98)天,平均住院(33.60±4.37)天。结论:本病患者临床表现多样,可见多个脏器受损。中西药配合中医辨证论治和中医心理干预有助于缓解患者临床症状,促进康复。 |
英文摘要: |
Objective: To understand the clinical manifestation of severe acute respiratory syndrome (SARS) and explore the effective treatment of integrative Chinese and western medicine (ICWM). Methods:The data of patients, whose diagnosis of SARS had been confirmed were summarized and analyzed, and clinical observation was conducted when the patients were treated with ICWM. Results: In early stage of 42 patients, the symptoms revealed were fever in 100% (of SARS patients, same hereafter), headache in 92.9%, aversion to cold in 76.2%, chest stuffiness in 76.2 % , cough in 73.8 % and myalgia in 88.1 % ; the pulmonary lesion involving ≥ 3 lobes in 42.9%, involving 2 lobes in 47.6% and 1 lobe in 9.5% ; 61.9% of them showed liver function abnormality (increase of ALT or AST), 47.6% showed elevated myocardial enzyme (CK or CK-MB), in their T-lymphocyte subsets, 91.1% (31/34 patients) with lowered CD3 and 76.5% (26/34 patients) with lowered CD4/CD8 ratio. In the mid-late stage, the symptoms were lassitude and weakness in 85. 7%, frightened feeling in 81.0%, short breath or chest stuffiness in 71.4%, loss of appetite in 64.3%, light dark tongue proper in 52. 4 % , yellow and white tongue coating in 45. 2 % , and middle-root part of tongue with yellow thick coating in 21. 4% . Most of them were asymptomatic during discharge from hospital, with their pulmonary lesion, showed by chest film, 92. 8% completely absorbed as well as normalized liver function, myocardial enzyme and renal function. However, in 30 patients, the CD3 was lower than normal range in 70% and CD4/CD8 inclined to lower margin in 36. 7%, follow-up on which should be taken care. In the 42 patients, who received western medicine (WM) alone in early stage and ICWM in mid-late stage, none of them died. The mean defervescent time was 3. 52±0. 85 days, the time for complete absorption of pulmonary lesion, judged by chest X-film, was 26.82±5.98 days, and the mean hospitalization time was 33. 6±4.37 days. Conclusion: The manifestation of SARS is multifarious, revealed damage of multiple organs. TCM according to Syndrome Differentiation and psychiatric intervention are beneficial to remiting partial symptoms and promoting rehabilitation. |
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