| 方向明,曹世宏.平喘合剂对实验性哮喘豚鼠嗜酸细胞阳离子蛋白、白细胞介素-5等的影响[J].中国中西医结合杂志,2003,(8):609-611 |
| 平喘合剂对实验性哮喘豚鼠嗜酸细胞阳离子蛋白、白细胞介素-5等的影响 |
| Effect of Pingchuan Mixture on Eosinophil Cation Protein and Interleukin-5 in Experimental Guinea Pigs with Asthma |
| 免费下载全文 查看/发表评论 下载PDF阅读器 |
| |
| DOI： |
| 中文关键词: 哮喘 炎症细胞计数 嗜酸细胞阳离子蛋白 白细胞介素-5 |
| 英文关键词:asthma inflammatory cell count eosinophil cation protein interleukin-5 |
| 基金项目: |
|
| 摘要点击次数: 1221 |
| 全文下载次数: 1459 |
| 中文摘要: |
| 目的 :观察平喘合剂对哮喘豚鼠血浆嗜酸细胞阳离子蛋白 (ECP)、支气管肺泡灌洗液 (BALF)中白细胞介素 5 (IL 5 )水平及炎症细胞计数变化的影响。方法 :采用常规计数法测BALF中嗜酸粒细胞、中性粒细胞、淋巴细胞计数 ,运用ELISA法测IL 5 ,放免法测ECP。结果 :治疗后平喘合剂、地塞米松组嗜酸粒细胞、中性粒细胞、淋巴细胞数量 ,ECP、IL 5水平比治疗前明显降低 (P <0 0 5或P <0 0 1) ,平喘合剂、氨茶碱、地塞米松、定喘止咳片各组间比较 ,差异均无显著性。结论 :平喘合剂可降低炎症细胞计数、ECP、IL 5而治疗哮喘。 |
| 英文摘要: |
| Objective:To observe the effect of Pingchuan Mixture (PCM) on plasma eosinophil cation protein (ECP), interleukin-5 in bronchial alveolar lavage fluid (BALF) and inflammatory cell count in experimental guinea pigs with asthma. Methods:The eosinophil, neutrophil, lymphocyte count were conducted by conventional method, IL-5 was detected by ELISA and ECP determined by RIA. Results:Levels of eosinophil, neutrophil, lymphocyte, ECP and IL-5 after treatment were significantly lower than those before treatment, the difference between groups treated respectively by PCM, aminophylline, dexamethasone and Dingchuan Zhike Tablet was insignificant. Conclusion:PCM could treat asthma by reducing the inflammatory cell count, ECP and IL-5. |
| 关闭 |
|
|
|
扫描微信二维码，获取更多信息