通脑活络针刺法治疗超早期、急性期脑梗死临床观察

作者	单位
李继英	南京市中医院脑血管病中心南京210001
彭宇竹	南京市中医院脑血管病中心南京210001
杨芳	南京市中医院脑血管病中心南京210001
刘孔江	南京市中医院脑血管病中心南京210001
杜新	南京市中医院脑血管病中心南京210001
黄迟	南京市中医院脑血管病中心南京210001
阮志忠	南京市中医院脑血管病中心南京210001
张晖	南京市中医院脑血管病中心南京210001

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中文摘要:

目的 :评价通脑活络针刺法治疗超早期 (<6h)和急性期 (6～ 4 8h)脑梗死的疗效及安全性。方法 :临床分为超早期和急性期两个时段 ,观察通脑活络针刺法 (治疗组 )、尿激酶 12 0万U即刻静脉溶栓法(对照组 ,急性期改为单纯体针法 )和 0 9%生理盐水 2 5 0ml静脉滴注法 (安慰剂组 )的临床疗效 (各组同时均采用低分子右旋糖酐注射液 14天、胞二磷胆碱 2 8天及肠溶阿司匹林 2 8天 )。结果 :超早期时段治疗组和对照组疗效比较差异无显著性。急性期时段通脑活络针刺法和单纯体针法疗效比较差异有显著性。颅内出血率 :超早期治疗组、安慰剂组及对照组分别为 3 3%、4 0 %及 8 0 %。结论 :超早期、急性期通脑活络针刺法治疗急性脑梗死是有效的 ,且安全性好。

英文摘要:

Objective: To evaluate the efficacy and safety of Tongnao Huoluo acupuncture (TNHLA) therapy in treating acute cerebral infarction at ultra-early stage (within 6 hrs after attack) or acute stage (within 6-48 hrs after attack). Methods: The effect of TNHLA in the two stages was observed separately (treated group) and compared with the effect treated with immediate thrombolysis by intravenously given urokinase 12 million units in ultra-early stage or simple body acupuncture in acute stage (control group), and with those treated with intravenous dripping of normal saline (placebo group). In the meantime, all groups treated with low molecular dextran injection for 14 days, cytidine diphosphate choline and entric soluble aspirin for 28 days. Results: Effect of TNHLA in the treated group was insignificantly different to that after thrombolysis of the control group in the ultra-early stage, but significantly higher than that of body acupuncture in acute stage. The intracranial hemorrhage rates in the treated, control, and placebo group were 3.3%, 4.0%, and 8.0% respectively. Conclusion: TNHLA is effective and safe in treating acute cerebral infarction at ultra-early stage or acute stage.

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