| 黄俊山,林求诚,黄荣璋,郑关毅,林智颖.元通胶囊治疗血管性痴呆的临床研究[J].中国中西医结合杂志,2003,(11):815-818 |
| 元通胶囊治疗血管性痴呆的临床研究 |
| Clinical Study on Effect of Yuantong Capsule in Treating Vascular Dementia |
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| DOI： |
| 中文关键词: 元通胶囊 血管性痴呆 经颅血管彩色多普勒 血栓素A2 前列环素 内皮素 一氧化氮 |
| 英文关键词:Yuantong Capsule vascular dementia transcranial color Doppler thromboxane A2 prostacy- clin endothelin nitrogen monoxide |
| 基金项目:福建省卫生厅中医药重点资助课题(No.104) |
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| 中文摘要: |
| 目的:观察元通胶囊治疗血管性痴呆(VD)的临床疗效。方法:将83例VD患者按2:1比例随机分为两组。治疗组(54例)用元通胶囊,每次3粒,每日3次口服;对照组(29例)予喜得镇,每次2mg,每日3次口服,两组疗程均为2个月。结果:总有效率治疗组(92.6％)明显优于对照组(72.4％,P<0.01);在智能量表积分、生活自理能力积分、中医症状积分和实验室指标等方面,治疗组均优于对照组,两组比较差异有显著性(P<0.05或P<0.01)。结论:元通胶囊为治疗血管性痴呆的有效药物。 |
| 英文摘要: |
| Objective: To observe the clinical effect of Yuantong Capsule (YTC) in treating vascular dementia (VD). Methods: Eighty-three patients of VD were randomized on ratio of 2:1 into two groups, the 54 patients in the treated group were treated with YTC orally administered, 3 times a day, 1 capsule in each time. The remaining 29 patients in the control group were treated with Hydergine orally, 3 times a day, 2 mg in each time. The therapeutic course for both groups was 2 months. Results: The therapeutic effect in the treated group was significantly better than that in the control group, significant difference (P<0.05 or P <0.01) was shown in comparison of the two groups in terms of the mini-mental state examination (MMSE) and activity of daily living (ADD test, symptoms scoring, total effective rate, and laboratory indexes findings. Conclusion: The therapeutic effect of YTC in treating VD was obvious. |
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