400例更年期综合征临床证候辨证标准现场调查分析

作者	单位
申春悌	江苏省常州市中医医院
张华强	南京中医药大学附属医院
朱雄华	江苏省常州市中医医院
常惠	江苏省常州市中医医院
陈启光	东南大学公共卫生学院
闵婕	东南大学公共卫生学院

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中文摘要:

目的通过更年期综合征的临床流行病学调查 ,探讨临床证候辨证标准研究的思路和方法。方法采用DME(designmeasurementevaluation)设计方法对 4 0 0例更年期综合征的现场调查资料进行盲法的统计学处理和分析 ,采用因子分析和结构方程模型 ,研究本病的证候分布及各证所包含的四诊信息及实验室检测指标。结果更年期综合征的证型可归为肝阳上亢证、肾阳亏虚证、肝肾阴虚证、肝郁伤神证。结论病证辨证标准研究的思路是在回顾性研究的基础上确定病中证的假设辨证标准进行现场调查 ,采用聚类分析、因子分析、临界理论确定病中证类分布及临界证、典型证、兼夹证、鉴别诊断指标 ,制订新的辨证标准。

英文摘要:

ObjectiveTo explore the thinking and method of studying the diagnostic standard for TCM Syndrome Differentiation by means of clinical epidemiological investigation on climacteric syndrome. MethodsAdopting DME (design measurement evaluation), the field investigation data of 400 patients with climacteric syndrome were statistically managed and analyzed using blind method. The distribution of syndromes, including information of four diagnosis of various syndromes as well as the laboratory findings in patients were studied using factor analysis and model of structural equation. ResultsThe Syndrome types of climacteric syndrome were identified as the Gan Yang exuberance type, the Shen Yang deficiency type, the Gan Shen Yin deficiency type and the Gan stagnancy injuring Spirit type. ConclusionThinking of the diagnostic standard study for TCM Syndrome Differentiation is to identify the supposed diagnostic standard of a disease based on retrospective study, to formulate a new hypothetical standard of Syndrome by way of field investigation, category analysis, factor analysis, and critical theory, followed with identification of Syndrome distribution in the disease, its critical syndrome, typical syndrome, complicated syndrome, and criteria for Syndrome Differentiation.

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