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沈自尹.系统生物学和中医证的研究[J].中国中西医结合杂志,2005,(3):255-258
系统生物学和中医证的研究
Study on Systematic Biology and Syndrome of Traditional Chinese Medicine
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DOI:
中文关键词:  系统生物学  还原论  涌现论  中医证  数学建模
英文关键词:systematic biology  reduction theory  emergency theory  TCM syndrome  mathematical modeling
基金项目:国家自然科学基金项目 (No .90 4 0 90 0 1 0 ) ;上海市科委重点基础研究基金项目 (No.0 4JC1 4 0 90 )
作者单位
沈自尹 复旦大学附属华山医院中西医结合研究所 上海200040 
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中文摘要:
      对自 15世纪下半叶以来科学思想和科学方法论的回顾 ,阐明还原论是研究存在的科学 ,而涌现论则是生成的观点 ,科学的态度是把还原论和整体论结合起来 ,指出系统生物学理论和分子生物学相结合 ,以及数学建模的方法是生命科学研究的新趋势 ,而“证”的研究正好和这个处于科学前沿、综合程度很强的系统生物学理论相结合 ,将几十年来用还原论方法在分子水平的研究成果用生物数学方法进行系统整合 ,将再次把“证”的研究推向科学前沿
英文摘要:
      The ideas and methodology of science since the later half of 15th century were reviewed in this article. It was indicated that reduction theory is the science studying existence, mainly the components and nature of things, and emergency theory is the science studying production, mainly involved in the production of new things, the scientific attitude in research work is to combine these two theories (the reductionism and holism). The author also pointed out that the combination of systematic biology with molecular biology, and the application of mathematical modeling are the new trend in research of life science. Research of "syndrome", a professional TCM term, is just consistent with this located at scientific frontier and highly comprehensive systematic biological theory. The integration of findings at molecular level obtained during the last several decades by reduction theory will push the research of "Syndrome" into the scientific frontier again.
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