大黄、三七粉治疗肾综合征出血热腔道出血的疗效观察

Observation on Therapeutic Effect of Rhubarb and Sanchi Powder in Treating Patients with Hemorrhagic Fever in Nephrotic Syndrome Complicated with Digestive Tract Bleeding

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中文关键词: 大黄三七肾综合征出血热腔道出血

英文关键词:rhubarb sanchi hemorrhagic fever in nephrotic syndrome digestive tract bleeding

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作者	单位
付德才	牡丹江医学院附属红旗医院黑龙江157011
于春艳	牡丹江医学院附属红旗医院黑龙江157011

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中文摘要:

目的研究中药大黄、三七粉对肾综合征出血热腔道出血的治疗作用。方法将临床诊断为肾综合征出血热伴腔道出血患者60例随机分为2组。治疗组31例,予大黄3g、三七2g,研成细末混匀,每日3~4次口服,对照组29例,予止血敏2g,每日1次静脉滴注。结果治疗组痊愈17例,显效5例,有效6例,愈显率为70.97%,总有效率90.32%;对照组痊愈10例,显效3例,有效6例,愈显率为44.83%,总有效率65.52%。两组比较,差异有显著性(P<0.05,P<0.01);治疗组平均止血时间为(2.32±0.82)h,血小板计数为(8.84±1.13)×109/L及血小板聚集率明显提高,与对照组〔分别为(4.15±0.69)h,(6.22±0.89)×109/L〕比较,差异均有显著性(P<0.01)。结论大黄、三七粉有促进血管收缩,缩短出血时间及止血作用,可增加血小板数量,提高血小板聚集功能。

英文摘要:

ObjectiveTo observe the therapeutic effect of rhubarb and Sanchi Powder (RSP) in treating patients with hemorrhagic fever in nephrotic syndrome (NS) complicated with digestive tract bleeding. MethodsSixty patients clinically diagnosed as hemorrhagic fever in NS complicated with digestive tract bleeding were randomized into 2 groups. Fine ground rhubarb (3g) and SP (2g) were given orally to the patients in the treated group 3-4 times daily. Dicynonum (2g) was given by intravenously dripping to the patients in the control group. ResultsIn the treated group, 17 patients were cured, 5 markedly effective and 6 effective, with the markedly effective rate of 70.97% and the total effective rate of 90.32%. The corresponding number in the control group was 10,3,6,44.83% and 65.52%, respectively, significant difference was shown in comparison between the two groups (<0.05 or <0.01). The average hemostatic time was (2.32±0.82)h, the platelet count was (8.84±1.13)×10~9/L,and the platelet aggregation rate was obviously improved in the treated group, which were significantly different to those in the control group 〔(4.15±0.69)h, (6.22±0.89)×10~9/L, respectively, <0.01〕. ConclusionRSP has the action of promoting vasoconstriction, shortening the bleeding time and blood arresting, it can increase the platelet count and improve the platelet aggregation.

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