强骨胶囊治疗骨质疏松性桡骨远端骨折的临床观察

作者	单位
马树强	西安交通大学第二医院骨科西安710004
王坤正	西安交通大学第二医院骨科西安710004
党晓谦	西安交通大学第二医院骨科西安710004
张明宇	西安交通大学第二医院骨科西安710004

摘要点击次数: 1290

全文下载次数: 1126

中文摘要:

目的探讨强骨胶囊治疗对骨质疏松性桡骨远端骨折患者骨密度(BMD)及骨折愈合的影响。方法对65例原发骨质疏松性桡骨远端骨折患者手法整复固定后,测定患者股骨颈骨密度值,随机将患者分为治疗组(33例)及对照组(32例)。治疗组强骨胶囊每次1粒(180mg)口服,每日3次;对照组迪巧维D钙咀嚼片每次2片(1500mg)口服,每日1次,两组共服用药物3个月。患者每月行X线照片检查,观察骨折断端骨痂生长情况并进行疗效对比;治疗3个月后再次测定股骨颈骨密度值并进行比较。结果治疗组治疗2个月后,与对照组比较,骨痂形成时间短、数量明显增加,骨皮质增厚;治疗组骨折愈合时间为(9.4±2.5)周,对照组骨折愈合时间(12.5±2.9)周,两组差异有显著性(P<0.05);治疗组骨密度治疗前(0.621±0.085)g/cm2,治疗后(0.646±0.090)g/cm2,治疗前后差异有显著性(P<0.05);对照组治疗前后无明显差异(P>0.05);两组治疗后比较,差异有显著性(P<0.05)。结论强骨胶囊治疗骨质疏松性桡骨远端骨折,能促进骨痂提早形成,增加骨痂生成的数量,增加骨密度,改善骨结构,减少外固定时间。

英文摘要:

Objective To explore the effects of Qianggu Capsules (QGC) on the fracture healing and the bone mineral density (BMD) in radius distal osteoporosis fracture (RDOF) patients. Methods Bone mineral density (BMD) of femoral neck in 65 patients with RDOF was detected after the fracture was fixed manually. They were then randomly divided into two groups. Thirty-three patients in the treated group took QC, 1 capsule (180mg) each time, three times a day, while 32 patients in the control group took D-Cal Biocal 2 tablets (1500 mg) each time, once daily. The therapeutic course for both groups was three months. X-ray examination on the broken end of the fractured bone was taken every month to observe the bony callus formation for comparing the curative effect, and BMD of femoral neck were detected again after patients were treated for 3 months. Results The bony callus appeared earlier, more in volume with thicker cortex in the treated group after 2 months of treatment versus that in the control group. The fracture healing time in the treated group was 9.4±2.5 weeks and that in the control group was 12.5±2.9 weeks, showing significant difference between them(P<0.05). BMD in the treated group before treatment was 0.621±0.085 g/cm2, which was lower than that after treatment (0.646±0.090g/cm2) with significant difference showing between them(P<0.05), while no significant change of BMD was found in the control group between before and after treatment, and significant difference was found in BMD between the two groups after treatment(P<0.05). Conclusion QGC can promote the formation of bony callus ahead of time, increase the volume of bony callus and BMD, improve the bone structure, and thus the time of external fixation in treating RDOF could be reduced.

关闭