益肾健脾化瘀汤治疗慢性肾功能不全的疗效观察

目的观察益肾健脾化瘀汤治疗慢性肾功能不全的疗效。方法选择慢性肾功能不全患者43例,随机分成两组,治疗组24例口服益肾健脾化瘀汤,对照组19例口服包醛氧淀粉,治疗2个月。观察治疗后的症状体征、肾功能、血脂和临床综合疗效。结果治疗组和对照组总有效率分别为87·5%(21/24例)及52·6%(10/19例),两组比较差异有显著性(P<0·05)。治疗组在改善肾功能、血脂、血液流变学等方面优于对照组(P<0·05)。结论益肾健脾化瘀汤治疗慢性肾功能不全疗效较好。

英文摘要:

Objective To observe the therapeutic effect of Yishen Jianpi Huayu Decoction (YJHD) in treating chronic renal insufficiency (CRI). Methods Forty-three patients with CRI were selected and randomly assigned into two groups, the 24 patients orally administered with YJHD in the treated group and the 19 administered with coated aldehyde oxystarch in the control group, the therapeutic course was 2 months. The symptom, physical sign, kidney function, blood lipids of patients were observed before and after treatment and the comprehensive clinical efficacy of the treatment was evaluated. Results The total effective rate was 87.5% and 52.6% in the two groups respectively, it was significantly higher in the treated group than that in the control group (P<0.05). The improvement of kidney function, blood lipids, and hemorrheologic parameters in the treated group were superior to those in the control group (P<0.05). Conclusion YJHD is effective in treating chronic renal insufficiency.

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