| 罗和春,钱瑞琴,赵学英,毕娟,信红岭,蒋学柱,许珂,阎少校.丹栀逍遥散治疗抑郁症的临床疗效观察[J].中国中西医结合杂志,2006,(3):212-214 |
| 丹栀逍遥散治疗抑郁症的临床疗效观察 |
| Clinical Observation on Effect of Danzhi Xiaoyao Powder in Treating D epr ession |
| 免费下载全文 查看/发表评论 下载PDF阅读器 |
| |
| DOI： |
| 中文关键词: 丹栀逍遥散 麦普替林 抑郁症 随机双盲对照研究 |
| 英文关键词:Danzhi Xiaoyao powder maprotiline depression randomized double-blinded contr olled study |
| 基金项目:教育部教育振兴行动计划特殊专项985一期 |
|
| 摘要点击次数: 2071 |
| 全文下载次数: 7 |
| 中文摘要: |
| 目的观察丹栀逍遥散治疗抑郁症的临床疗效及不良反应。方法采用随机双盲对照方法,将63例患者分为两组,分别用麦普替林(西药组31例)和丹栀逍遥散(中药组32例)治疗,于用药前及用药2、4、6周时采用汉米尔顿抑郁量表(HAMD)、抑郁自评量表(SDS)、焦虑自评量表(SAS)及中医症状辨证量表等评定药物疗效,用Asberg副反应量表评定不良反应。结果两组临床疗效比较差异无显著性;两组治疗后HAMD、SDS和SAS积分均明显低于治疗前(P<0.05),但两组间比较差异无显著性;中医症状辨证量表评定两组间差异无显著性;Asberg副反应量表分值中药组低于西药组(P<0.05)。结论丹栀逍遥散治疗抑郁症疗效与麦普替林相当,而不良反应明显少于麦普替林。 |
| 英文摘要: |
| ObjectiveTo observe the effect and side eff ect of Danzhi Xiaoyao powder (DXP) in treating depression. MethodsA randomized controlled and double-blinded stud y was conducted in 63 cases of depression by divided them into the western medi cine group (WMG, 31 cases) treated with maprotiline, and the Chinese medicine gr oup (CMG, 32 cases) treated with DXP. The effect of therapy was e valuated before and at the 2nd, 4th and 6th week of the treatment with Ha milton’s depressive scale (HAMD), self-rating depression scale (SDS), self-rat in g anxiety scale (SAS) and the scale for TCM syndrome and symptom d ifferentiation (TCM-SSD), and the side-effect of therapy was as se ssed with Asberg side-effect scale as well. ResultsTh ere was no significant difference between the two groupsin scores of HAMD, S DS, SAS, and TCM-SSD. The markedly effective rate in CMG wa s 84% and in WMG 87%, showed no significance between them ( P>0.05). The scores of HAMD, SDS and SAS of both groups were remarkably lowered a fter therapy (P<0.05). However, the score of Asberg in C MG was low er than that in WMG (P<0.05). Conclusion DXP shows the effect equivalent to that of maprotiline, but with obviously less side-effe ct. |
| 关闭 |
|
|
|
扫描微信二维码，获取更多信息