| 邓银泉,范小芬,吴国琳,熊福林.玉泉丸对2型糖尿病促炎细胞因子干预的影响[J].中国中西医结合杂志,2006,(8):706-709 |
| 玉泉丸对2型糖尿病促炎细胞因子干预的影响 |
| Effect of Yuquan Pill on Proinflammatory Cytokines in Patients with Type 2 Diabetes Mellitus |
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| DOI： |
| 中文关键词: 2型糖尿病 C反应蛋白 肿瘤坏死因子 白细胞介素-6 玉泉丸 |
| 英文关键词:type 2 diabetes mellitus C-reactive protein tumor necrosis factor-α interleukin-6 Yuquan Pill |
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| 摘要点击次数: 1508 |
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| 中文摘要: |
| 目的观察玉泉丸对2型糖尿病患者促炎细胞因子干预的影响。方法90例2型糖尿病患者按2∶1随机分成治疗组和对照组,两组均在饮食控制、运动等基础治疗基础上加用拜糖苹治疗,治疗组另加服玉泉丸,每次6g,1日4次,疗程3个月,同时观察其C反应蛋白(Creactiveprotein,CRP)、肿瘤坏死因子α(tumornecrosisfactorα,TNFα)、白细胞介素6(interleukin6,IL6)等促炎细胞因子的变化。结果治疗组CRP、TNFα、IL6水平均较治疗前显著降低(P<0.01),两组间CRP、TNFα、IL6治疗前后差值比较差异亦有显著性,治疗组均明显高于对照组(P<0.01)。结论玉泉丸能降低已升高的促炎细胞因子水平。 |
| 英文摘要: |
| ObjectiveTo observe the effect of Yuquan Pill (YP) on proinflammatory cytokines in patients with type 2 diabetes mellitus (DM2). MethodsNinety patients with DM2 were randomly divided into the treated group and the control group by the ratio of 2∶1. Both groups were treated with Glucobay on the base of dietary and exercise therapy for 3 months, with YP, given to the treated group additionally 6 g four times a day. And the changes of proinflammatory cytokines, including C-reactive protein (CRP), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6), etc. were observed. ResultsThe levels of serum CRP,TNF-α and IL-6 significantly lowered after treatment in both groups (P<0.01), and the improvement in the treated group was superior to that in the control group (P<0.01). ConclusionYP could reduce the levels of the increased proinflammatory cytokines in patients with DM2. |
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