清灵定眩汤治疗椎-基底动脉供血不足眩晕患者的临床观察

作者	单位
郑国庆	温州医学院附属第二医院脑科中心
王艳	广东省中医院神经内科
潘鹃	广东省中医院神经内科
黄培新	广州中医药大学附属第二医院

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中文摘要:

目的探讨清灵定眩汤治疗椎-基底动脉供血不足眩晕(VBIV)临床疗效。方法在中西医常规对症、支持基础上分别加用西比灵(对照组19例)及清灵定眩汤(治疗组20例)治疗2周,比较两组临床疗效及复发情况。结果治疗组临床疗效、复发率、症状评分、血液流变学及经颅多普勒指标改善均优于对照组(P<0·05或P<0·01)。结论清灵定眩汤对VBIV有明显的治疗作用,而改善微循环和降低血液黏度可能是其治疗学机制之一。

英文摘要:

ObjectiveTo observe the therapeutic effect of Qingling Dingxuan Decoction (QDD) on vertigo caused by insufficient blood-supply of ventebrobasilar artery (IBVA). Methods Thirty-nine patients were divided into the flunarizine group (n=19) and the QDD group (n=20) treated with respective medicine on the base of routine treatment with Chinese and Western medicine. The clinical efficacy and recurrent rate were observed and compared. Results Compared with those in the flunarizine group, clinical curative effect was better, recurrent rate lower, symptom score higher, hemorheological parameters and transcranial doppler indexes were improved more significant in the QDD group (P<0.01 or P<0.05). Conclusion QDD had obvious therapeutic effect on IBVA. Improvement of microcirculation and reduction of blood viscosity may be one of the therapeutical mechanisms.

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