肿瘤干细胞研究进展与扶助肾中精气抗癌

作者	单位
郑展	上海中医药大学附属龙华医院肿瘤科上海中医药大学肿瘤研究所
徐振晔	上海中医药大学附属龙华医院肿瘤科上海中医药大学肿瘤研究所

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中文摘要:

肿瘤中存在肿瘤干细胞,数目极少,却对肿瘤的发生起着决定性作用。肿瘤干细胞是一种特殊类型的干细胞,具备高度增殖能力与自我更新能力,其结果是维持肿瘤干细胞数目稳定并产生肿瘤。根治肿瘤的关键应是针对肿瘤干细胞。肿瘤干细胞起源于成体干细胞。中医学认为,正常干细胞可归于肾中精气的范畴,恶性肿瘤患者往往具有精气两亏之证,扶助肾中精气对治疗肿瘤有重要意义。

英文摘要:

The tumor stem cells (TSC) existing in the tumor plays a crucial role in carcinogenesis though very few in number. It is a special kind of stem cells with highly proliferative and self-regenerative cap ability to maintain its number stable and generate tumor. Therefore, the radical treatment of tumor should focus on TSC. TSC are derived from adult stem cells. According to TCM theory, normal stem cells belong to the category of Shen essence and qi, and patients suffering from malignant tumor always manifest as the syndrome of essence and qi deficiency, so nourishing Shen essence and qi should be of great importance for treatment of tumor.

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