降浊活血益肾汤治疗痛风45例临床观察

目的观察自拟降浊活血益肾汤与西药联合治疗痛风的作用。方法90例痛风患者随机分为两组,每组各45例,对照组急性期先口服芬必得,缓解期服别嘌呤醇;治疗组在对照组治疗的基础上同时口服降浊活血益肾汤,均治疗4周。比较两组临床疗效、急性期患者主要关节症状疗效、不同证型疗效、血尿酸变化、不良反应和复发情况。结果治疗组临床愈显率明显高于对照组(P<0·05);并且在降低血尿酸、改善急性期患者主要关节症状及疗效稳定性方面均优于对照组;对痛风不同证型的疗效基本一致,不良反应少。结论降浊活血益肾汤联合西药治疗痛风有良好的协同效应,能够降低血尿酸和改善症状。

英文摘要:

Objective To observe the curative effect of the self-formulated Jiangzhuo Huoxue Yishen Decoction(JHYD) combined with Western medicine in treatment of gout.Methods A total of 90 gout patients were randomly assigned to two groups,the control group(45 cases) administrated with Finbid orally in the acute stage and allopurinol in the remission period;and the treatment group(45 cases) treated with the same treatment plus oral administration of JHYD.The therapeutic course for both was 4 weeks.The total curative effect,the effect on main symptoms and on different syndrome types,changes of blood uric acid,adverse reactions and recurrence of gout were observed and compared between the two groups.Results The cured and markedly effective rate and the total effective rate in the treatment group were all obviously higher than those in the control group(P<0.05).And the effect was better in the treatment group in decreasing blood uric acid,improving symptoms of main joints and stabilizing the curative effect.The curative effect of the combined therapy on different syndrome types was basically consistent,and it showed few adverse reactions.Conclusion The self-formulated JHYD showed synergistic effect with Western medicine in treatment of gout,which could decrease blood uric acid level and improve clinical symptoms.

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