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张琼,陈家旭,于震.乳腺增生病肝郁气滞证心理应激生活事件的研究[J].中国中西医结合杂志,2007,(6):509-512
乳腺增生病肝郁气滞证心理应激生活事件的研究
Study on Mental Stress Life Events in Patients with Cyclomastopathy of Liver Stagnation Syndrome Type
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DOI:
中文关键词:  乳腺增生病  肝郁气滞证  心理应激  生活事件
英文关键词:cyclomastopathy  liver stagnation syndrome  mental stress  life events
基金项目:高等学校全国优秀博士学位论文作者专项资金资助(No.200059)
作者单位
张琼 北京大学药学院 北京100029 
陈家旭 北京大学药学院 北京100029 
于震 北京大学药学院 北京100029 
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中文摘要:
      目的观察乳腺增生病肝郁气滞证心理应激在生活事件上的变化。方法采用临床流行病学研究方法,研究辨证分型为肝郁气滞证和非肝郁气滞证的乳腺增生患者心理应激生活事件评分的改变。结果肝郁气滞证组患者平均年龄(33.38±6.76)岁低于非肝郁气滞证组(38.36±9.89)岁患者(P<0.01);肝郁气滞证中度(33.96±7.31)岁、重度(37.43±7.38)岁患者平均年龄高于轻度(31.67±5.39)岁患者(P<0.05,P<0.01)。肝郁气滞证组患者生活事件评分(32分)显著高于非肝郁气滞证组患者(22分,P<0.01);肝郁气滞证患者生活事件评分(分),中度34.69±17.78、重度51.65±20.75,显著高于轻度患者26.57±15.85;中、重度分别与轻度比较,差异有显著性(P<0.05,P<0.01);中度与重度比较,差异亦有显著性(P<0.01)。结论40岁以下是乳腺增生病的高发年龄,乳腺增生病患者属于肝郁气滞证者较多。年龄、生活事件评分可以成为乳腺增生病中医辨证分型和肝郁气滞证分级的客观依据。
英文摘要:
      Objective To observe the changes of mental stress life events (MSLE) in patients with cyclomastopathy of liver stagnation syndrome type (LSS). MethodsClinical epidemiological research method was adopted, the changes of MSLE were observed in cyclomastopathy patients of LSS or non-LSS, classified by syndrome differentiation of TCM. ResultsNot only the mean age (33.38±6.76 years) of patients with LSS was obviously lower than that of patients with non-LSS (38.36±9.89 years,P<0.01), but also the mean age of patients with moderate and serious symptoms of LSS (33.96±7.31 and 37.43±7.38 years) were higher than that of patients with mild symptoms of LSS(31.67±5.39 years, P<0.05 and P<0.01). MSLE score of patients with LSS (32 scores) was significantly higher than that of patients with non-LSS (22 scores, P<0.01). MSLE score of patients with moderate and serious LSS was 34.69±17.78 scores and 51.65±20.75 scores respectively, both were significantly higher than that of patients with mild LSS (26.57±15.85 scores, P<0.05 and P<0.01). ConclusionThe high incidence age of cyclomastopathy is under 40 years, and most of cyclomastopathy patients are classsified to LSS by TCM syndrome differentiation. So age and life event scores may be the objective bases for syndrome typing and liver stagnation syndrome grading in patients with cyclomastopathy.
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