中成药所致药疹162例临床分析

目的分析中成药所致药疹的特征及发生原因,为药疹的防治提供参考。方法回顾性分析162例中成药所致药疹患者的临床资料。结果中成药所致药疹主要为轻型药疹〔共161例,占99.4%〕;中药注射剂是诱发药疹的主要剂型〔共87例,占53.7%〕;联合用药者见多〔共106例,占65.4%〕;首次发生药疹确诊者少〔共14例,占8.6%〕。结论提高中成药所致药疹的认识,慎用中药注射剂,减少联合用药,详细询问用药史,可以有效的预防药疹发生。

英文摘要:

Objective To analyze the pathogenesis and characteristics of drug eruption induced by Chinese patent medicine for providing some referential materials on prevention and treatment of drug eruption.Methods Clinical data of 162 patients suffered from drug eruption were analyzed retrospectively.Results Most the drug eruption(161 times/case,accounting for 99.4%)belonged to the mild type;injection was the dominating dosage-form for inducing drug eruptions(87 times/case,53.7%);most of the cases occurred when drugs were used in combination(106 times/case,65.4%);and few of the patients(14 times/case,8.6%)had drug eruption for the first time.Conclusion Prevention of drug eruption could be realized by way of learning more relevant knowledge,cautiousl accepting the Chinese herbal injection,avoiding drug combination,as well as inquiry for the history of drug application of patients in detail.

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