解毒疏络法对55例肺癌患者放疗后生活质量的影响

目的观察解毒疏络法对肺癌患者放疗后生活质量的影响。方法设立单纯放疗组(对照组)53例,放疗加解毒疏络法组(治疗组)55例。以KPS评分、QLQ-C30生活质量调查问卷、LC13肺癌特异量表、中医疗效评定标准、6min步行距离及体重为指标进行临床疗效观察。结果KPS评分治疗组55例,有效13例(23.6%)、稳定27例(49.1%)、下降15例(27.3%),对照组53例,有效7例(13.2%)、稳定21例(39.6%)、下降25例(47.2%),两组比较,差异有统计学意义(P<0.05);QLQ-C30生活质量调查问卷及LC13肺癌特异量表评分,治疗组优于对照组(P<0.05);中医症状积分治疗组(24.52±6.98)较对照组(29.76±7.09)低(P<0.05);6min步行距离治疗组〔(233.4±29.2)m〕较对照组〔(205.8±31.9)m〕长(P<0.05);治疗组体重增加11例(20.0%)、稳定28例(50.9%)、减轻16例(29.1%),对照组体重增加5例(9.4%)、稳定26例(49.1%)、减轻22例(41.5%),两组比较,差异有统计学意义(P<0.05)。结论解毒疏络法可一定程度地改善放疗患者的生活质量。

英文摘要:

Objective To observe the effect of TCM therapy for removing toxic substance and unblocking meridians on post-radiation quality of life(QOF)in 55 patients with lung cancer.Methods All patients were randomly assigned to two groups,the 55 patients in the treated group were treated with radiotherapy combined with the TCM therapy,and the 53 in the control group were given radiotherapy alone.The clinical efficacy was evaluated by indexes including KPS scores,QLQ-C30 questionnaire,LC13 specific scale for lung cancer,evaluation criteria for TCM efficacy,the 6-min walking distance,and body weight,etc.Results The KPS score in the treated group after treatment was improved in 13 patients(23.6%),stabilized in 27(49.6%)and declined in 15(27.3%),while in the control group,it was improved in 7(13.2%),stabilized in 21(39.6%)and declined in 25(47.2%),the difference between the two groups was significant(P<0.05).The results from evaluation with QLQ-C30 questionnaire and LC30 scale in the treated group was also superior to those in the control group(P<0.05),respectively.The scores of TCM efficacy(24.52±8.98 vs 29.76±7.09,P<0.05)and the 6-min walking distance(233.4±29.2 m vs 205.8±31.9 m,P<0.05)were better in the treated group.After treatment in the treated group,the body weight was increased in 11 patients(20.0%),stabilized in 28(50.9%)and decreased in 16(29.1%),while in the control group it was increased in 5(9.4%),stabilized in 26(49.1%)and decreased in 22(41.5%),difference between the two groups was significant,too(P<0.05).Conclusion TCM therapy for removing toxic substance and unblocking meridians can improve the post-radiation QOL of patients with lung cancer to some extent.

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