和胃消痞胶囊治疗动力障碍性功能性消化不良的临床观察

作者	单位
夏立营	中国中医科学院西苑医院中医药保健研究中心
葛文津	中国中医科学院西苑医院中医药保健研究中心
刘维佳	中国中医科学院西苑医院中医药保健研究中心
周佩云	中国中医科学院西苑医院中医药保健研究中心
李明喜	中国中医科学院西苑医院中医药保健研究中心
崔坤敏	中国中医科学院西苑医院中医药保健研究中心

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中文摘要:

目的观察和胃消痞胶囊对动力障碍性功能性消化不良(FD)的疗效。方法将63例动力障碍性FD患者随机分为治疗组(33例)和对照组(30例)。治疗组给予和胃消痞胶囊治疗;对照组给予吗丁啉治疗,疗程均为4周。观察两组临床疗效及治疗前后胃电图变化。结果治疗后两组症状均较治疗前明显好转,治疗组痊愈3例,显效11例,有效14例,无效5例,对照组痊愈1例,显效8例,有效14例,无效7例,两组疗效比较差异无统计学意义。餐后正常慢波(%)治疗组治疗前为41.93±18.22,治疗后为50.86±16.03,治疗前后比较差异有统计学意义(P<0.05);对照组治疗前后无明显变化(P>0.05)。结论和胃消痞胶囊对动力障碍性FD患者有明显疗效。

英文摘要:

ObjectiveTo study the effect of Hewei Xiaopi Capsule(HXC) in treating patients with dyskinesis functional dyspepsia(FD).MethodsSixty-three patients with FD were randomly assigned to two groups,33 in the treated group and 30 in the control group,who were treated respectively with HXC and domperidone for 4 weeks to observe the clinical effect and changes in electrogastrogram(EGG) before and after treatment.ResultsSymptoms were alleviated in both groups after treatment,3 patients in the treated group were cured,the efficacy was judged as markedly effective in 11,effective in 14 and ineffective in 5,while in the control group,1 cured,8 markedly effective,14 effective and 7 ineffective,difference between the two groups showed no statistical significance.EGG showed that in the treated group,the normal slow-wave percentage was 41.93±18.22 before treatment and 50.86±16.03 after treatment,showing significant difference(P<0.05).ConclusionHXC is markedly effective in treating patients with FD.

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