| 连方,孙振高,张建伟,滕依丽,张宁,贺瑞燕,李婷婷.中药联合体外受精-胚胎移植治疗多囊卵巢综合征临床研究[J].中国中西医结合杂志,2008,(11):977-980 |
| 中药联合体外受精-胚胎移植治疗多囊卵巢综合征临床研究 |
| Combined Therapy of Chinese Medicine with in vitro Fertilization and Embryo Transplantation for Treatment of Polycystic Ovarian Syndrome |
| 免费下载全文 查看/发表评论 下载PDF阅读器 |
| |
| DOI： |
| 中文关键词: 中药 体外受精-胚胎移植 多囊卵巢综合征 补肾调冲 |
| 英文关键词:Chinese drug in vitro fertilization and embryo transplantation polycystic ovarian syndrome reinforeing Shen and regulating Chaong channel |
| 基金项目: |
|
| 摘要点击次数: 1600 |
| 全文下载次数: 4 |
| 中文摘要: |
| 目的评价补肾调冲中药联合体外受精-胚胎移植(IVF-ET)治疗多囊卵巢综合征(PCOS)患者的有效性。方法将64例行IVF-ET的PCOS患者按随机数字表法分为观察组(36例)和对照组(28例),观察组加服补肾调冲中药二至天癸颗粒。结果注射绒毛膜促性腺激素(HCG)日子宫内膜分型,观察组A级分型所占的比例为75.0%(27/36),对照组为42.9%(12/28),两组比较差异有统计学意义(P<0.01);观察组的优质卵率、受精率、优质胚胎率、临床妊娠率及卵巢过度刺激综合征(OHSS)发生率分别为(76.8±8.2)%、(73.5±8.9)%、(89.4±14.4)%、36.11%(13/36)及5.56%(2/36);而对照组分别为(64.4±8.7)%、(68.2±10.0)%、(79.5±15.2)%、21.43%(6/28)及10.71%(3/28),两组比较差异均有统计学意义(P<0.05);促性腺激素(Gn)用量,观察组为(33.8±12.5)支,对照组为(47.6±18.2)支(每支75IU),两组比较差异有统计学意义(P<0.01);取卵数目两组比较差异无统计学意义。结论在IVF-ET过程中联合应用补肾调冲中药可减少Gn用量,提高临床妊娠率。 |
| 英文摘要: |
| Objective To evaluate the validity of Chinese drugs for reinforcing Shen and regulating Chong channel(RSRCC)on patients with polycystic ovarian syndrome(PCOS)undergoing in vitro fertilization and embryo transplantation(IVF-ET).Methods Sixty-four patients with PCOS undergoing IVF-ET were randomly assigned to two groups,the treated group(36 cases)and the control group(28 cases),to the former,Chinese recipe for RSRCC was given additionally.Results On the human chorionic gonadotrophin(HCG)injecting day,the percentage of three-line sign of endometrium(type A)in the treated group was 75.0%(27/36),which was higher than that in the control group(42.9%,12/28),showing significant difference between the two groups(P<0.01).The rates of mature oocytes,fertilization,high-qualified embryo rate,clinical pregnancy rate and incidence rate of ovary hyper-stimulating syndrome(OHSS)in the treated group were(76.8±8.2)%,(73.5±8.9)%,(89.4±14.4)%,36.11%(13/36)and 5.56%(2/36),respectively;whereas those in the control group(64.4±8.7)%,(68.2±10.0)%,(79.5±15.2)%,21.43%(6/28)and 10.71%(3/28);the dosage of gonadotrophin administered in the treated group was 33.8±12.5 ampoules,and in the control group 47.6±18.2 amp oules,statistical significance was shown between groups in comparing all the above-mentioned parameters(P<0.05,P<0.01).However,the number of oocytes obtained in the two groups was insignificantly different(P>0.05).Conclusion Combined use of Chinese drugs for RSRCC in IVF-ET can reduce the dosage of gonadotrophin administered and raise the clinical pregnant rate. |
| 关闭 |
|
|
|
扫描微信二维码，获取更多信息