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杨涛,张兴桥,冯勇伟,徐海蓉,刘志顺,赵宏,叶永铭,王蕊,刘元石.电针治疗良性前列腺增生症93例疗效观察[J].中国中西医结合杂志,2008,(11):998-1000
电针治疗良性前列腺增生症93例疗效观察
Efficacy of Electroacupuncture in Treating 93 Patients with Benign Prostatic Hyperplasia
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DOI:
中文关键词:  电针  前列腺增生  中髎  会阳
英文关键词:electroacupuncture  prostatic hyperplasia  Zhongliao(BL33)acupoint  Huiyang(BL35)acupoint
基金项目:国家中医药管理局资助项目(No.04-05LP51)
作者单位
杨涛 中国中医科学院广安门医院 
张兴桥 河北省冀州市医院 
冯勇伟 北京中医药大学附属北京护国寺中医医院 
徐海蓉 中国中医科学院广安门医院 
刘志顺 中国中医科学院广安门医院 
赵宏 中国中医科学院广安门医院 
叶永铭 中国中医科学院广安门医院 
王蕊 中国中医科学院广安门医院 
刘元石 中国中医科学院广安门医院 
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中文摘要:
      目的评价电针治疗良性前列腺增生症的疗效。方法采用前瞻性多中心RCT研究设计,93例患者随机分成电针组47例及药物组46例;电针组取穴中髎、会阳,每次30min,隔日1次;药物组口服盐酸特拉唑嗪(马沙尼)2mg,每晚1次;治疗4周,疗效指标为国际前列腺症状评分(I-PSS)、泌尿症状困扰积分(BS)、最大尿流率(Qmax)、残余尿(PVR)和前列腺体积;并记录24h憋尿困难次数及夜尿次数。结果91例患者完成试验,两组均可降低I-PSS评分、提高Qmax、减少PVR、改善BS评分、减少24h憋尿困难次数及夜尿次数(P<0.01)。两组治疗前后前列腺体积比较差异无统计学意义。两组观察指标差值的组间比较:I-PSS评分电针组(6.52±0.41)优于药物组(2.69±0.36,P<0.01);Qmax(mL/s)电针组(4.71±0.70)提高优于药物组(1.75±0.55,P=0.001);PVR(mL)电针组(44.79±9.73)减少优于药物组(16.97±4.75,P=0.012)。结论电针中髎、会阳穴可显著改善轻中度良性前列腺增生患者的排尿困难症状,增加最大尿流率,减少残余尿,疗效优于盐酸特拉唑嗪。
英文摘要:
      Objective To evaluate the effect of electroacupuncture(EA)on symptomatic benign prostatic hyperplasia(BPH).Methods By prospective multi-centered randomized controlled design,93 patients with BPH were assigned to two groups,47 in the EA group treated by EA,and 46 in the control group treated by terazosin 2 mg taken orally once every evening.EA was applied on acupoints Zhongliao(BL33)and Huiyang(BL35),for 30 min,once every two days.The total treatment period was 4 weeks for them all.The indexes for efficacy evaluation were the International Prostatic Symptom Score(IPSS),the urinary symptom bother score(BS),the maximal urinary flow rate(Qmax),the post-voided residual urine volume(PVR),and the size of prostate gland.And the times of difficulties for holding urine in 24 h(HU)and the times of night-urinating(NU)were recorded as well.Results The trial was completed in 91 patients.After 4 weeks of treatment,the IPSS lowered,Qmax increased,PVR decreased,BS score reduced,times of HU and NU lessened in both groups(P<0.01).However,comparisons between groups showed that the improvement of IPSS(6.52±0.41 vs 2.69±0.36,P<0.01),Qmax(4.71±0.70 vs 1.75±0.55,P=0.001)and PVR(44.79±9.73 vs 16.97±4.75,P=0.012)was more significant in the EA group than in the control group respectively,but the size of prostate gland after treatment was not different between groups.Conclusion EA at Zhongliao and Huiyin points can markedly improve the symptoms of difficult urination in mild or moderate patients with BPH,increase their Qmax and reduce PVR.Its efficacy is better than that of terazosin.
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