莲黄汤治疗母儿ABO血型不合的临床疗效观察

作者	单位
蔡珠华	温州医学院附属第三医院瑞安市人民医院
陈颖异	温州医学院附属第三医院瑞安市人民医院
曾珏	温州医学院附属第三医院瑞安市人民医院
钱定良	温州医学院附属第三医院瑞安市人民医院
谢丽华	温州医学院附属第三医院瑞安市人民医院
周淑春	温州医学院附属第三医院瑞安市人民医院

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中文摘要:

目的观察莲黄汤治疗母儿ABO血型不合的临床疗效。方法对60例母儿ABO血型不合的孕妇随机分为两组,A组采用莲黄汤加减治疗,B组采用西医治疗,随访疗效。结果两组抗体效价均有不同程度的下降,A组有效率为90.0%,B组有效率为56.7%。A组新生儿平均脐血胆红素低于B组,差异有统计学意义(P<0.01)。两组新生儿5 min Apgar评分、体重及脐血血红蛋白含量差异均无统计学意义(P>0.05)。结论莲黄汤治疗母儿ABO血型不合有较好的疗效,能有效降低其血清抗体效价,预防产后新生儿ABO溶血病的发生。

英文摘要:

Objective To investigate the clinical curative effect of Lianhuang Decoction(LHD) in treating fetomaternal ABO blood group incompatibility(FM-ABOI).MethodsSixty pregnancy women diagnosed as FM-ABOI were randomly assigned to two groups,Group A treated with LHD and Group B treated with Western medicine.The therapeutic efficacy in the two groups was observed.ResultsThe antibody titer decreased after treatment in both groups to different extent;the effective rate was 90.0% in Group A and 56.7% in Group B.The bilirubin level in cord blood of Group A was lower than that in Group B significantly(P<0.01).No statistically significant difference was found between the two groups new-born in terms of 5-minute Apgar score,body weight and hemoglobin content in cord blood(P>0.05).ConclusionLHD has good clinical curative effect in treating FM-ABOI,could decrease the serum antibody titer,and prevent the occurrence of postpartum hemolytic disease in newborns.

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