中西药物相互作用探讨

作者	单位
龙项	湖南省岳阳市第二人民医院药剂科
李浩	湖南省岳阳市第二人民医院药剂科
湛延风	湖南省岳阳市第二人民医院药剂科
冯默	湖南省岳阳市第二人民医院药剂科

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中文摘要:

本文分别从中、西药物本身特点及药动学、药效学方面对中西药物相互作用进行探讨,为临床合理用药提供科学依据。中西药物间存在配伍上和药理学上的相互协同、相互制约;合用可能增加或减少不良反应,甚至发生毒性反应。中西药物合用时,应了解组方中各种药物化学成分的性质及药理作用,进行最佳的合并应用,避免不良的药物相互作用,以达到提高疗效、安全无害的目的。

英文摘要:

To study the interaction of traditional Chinese medicines and Western drugs in the interest of the interaction of Chinese and Western drugs viewing from their own characteristics,pharmacokinetics and pharmacodynamics to provide a scientific basis for rational clinical utilization of drugs.Pharmacological mutual coordination and/or restriction existed between the two kinds of drugs.When they were used in combination,it would increase or decrease adverse reactions,or even toxic reaction.When traditional Chinese drugs were used in combined with Western drugs,it is ought to know the nature and pharmacological effect of various chemical constituents in the compound for the best combination,try to avoid adverse drug interactions for the sake of reaching the goal of high effectiveness,safety and harmlessness.

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