电针治疗肿瘤患者口服硫酸吗啡控释片所致便秘的临床研究

目的观察电针治疗肿瘤患者口服硫酸吗啡控释片所致便秘的疗效。方法将66例口服硫酸吗啡控释片所致便秘的肿瘤患者,随机分为治疗组和对照组,各33例,治疗组采用电针双侧天枢穴和双侧足三里穴治疗,对照组采用口服枸橼酸莫沙必利片治疗,观察两组总体疗效和便秘症状评分。结果两组治疗后排便频率、排便时间、排便困难程度及大便性状评分均改善(P<0.01,P<0.05);治疗组、对照组治疗后便秘总评分分别为5.52±1.54、5.70±2.49,两组比较差异有统计学意义(P<0.01);总有效率治疗组97.0%,对照组87.9%。结论电针治疗肿瘤患者口服硫酸吗啡控释片所致便秘疗效显著。

英文摘要:

Objective To observe the effect of electro-acupuncture(EA)for treatment of morphine sulfate caused constipation in tumor patients.Methods Sixty-six tumor patients suffering from constipation caused by oral taking of morphine sulfate controlled-release tablet were equally randomized into the treated group treated with EA [on the bilateral Zusanli(ST36)and Tianshu(ST25)points] and the control group treated with citrate-mosapride tablet.The overall therapeutic effect and scores of constipation in both groups were estimated after treatment.Results Scores of constipation in terms of frequency,time,and difficulty degree of defecation,as well as stool properties,were all improved in both groups after treatment(P<0.01,P<0.05);the total score of constipation was 5.52±1.54 and 5.70±2.49 in the two groups respectively,which in the treated group was better,and showed significant difference compared with the score in the control group(P<0.01).The overall effective rate was 97.0% in the treated group and 87.9% in the control group.Conclusion EA has a good effect in treating constipation caused by oral taking of morphine sulfate controlled-release tablet.

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