王阶,林洪生,汤艳莉.艾滋病免疫重建相关影响因素探讨[J].中国中西医结合杂志,2009,(12):1125-1129 |
艾滋病免疫重建相关影响因素探讨 |
Immune Reconstitution Related Factors in Patients with HIV/AIDS |
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DOI: |
中文关键词: 艾滋病 免疫重建 高效抗逆转录病毒疗法 中医药 |
英文关键词:acquired immunodeficiency syndrome immune reconstitution highly active anti-retroviral therapy Chinese medicine |
基金项目:国家科技重大专项基金资助课题——中医药干预对艾滋病免疫重建的研究(No.2008ZX10005-004) |
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中文摘要: |
艾滋病患者在接受高效抗逆转录病毒疗法后,部分患者可以产生免疫重建现象,而影响免疫重建的因素极其复杂,人口学因素、人类免疫缺陷病毒(HIV)病情阶段、治疗类型、合并感染、基线CD+4T细胞水平、异常免疫激活、相关免疫表型及病原学因素等原因都可能对免疫重建造成影响,中医药对促进免疫重建具有一定作用。本文对以上因素的临床证据做简要归纳,为中医药介入艾滋病免疫重建的研究提供参考。 |
英文摘要: |
Immune reconstitution could be found in part of HIV/AIDS patients after receiving highly active anti-retroviral therapy(HAART).Its influencing factors are very complex.Many factors,such as the demographic factor,stage of HIV disease,pattern of therapy,sort of co-infections,baseline of CD+4 T-cell count,abnormal immune activation,related immune phenotype,and virologic factors,all could influence the immune reconstitution.In view of Chinese medine(CM) may play a positive role in this process,the clinical evidences for above-mentioned factors were summed up briefly in this paper for providing reference to the future studies on immune reconstitution with intervention of CM. |
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