1163例非酒精性脂肪性肝病患者体质类型分布特点及其与体重指数、血脂及肝功能酶学的关系

Study on Somato-type Distribution and Its Correlations with Body Mass Index,Blood Lipids and Hepato-enzymes in 1 163 Patients with Non-alcoholic Fatty Liver Disease

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中文关键词: 非酒精性脂肪性肝病中医体质体重指数血脂肝功能酶学

英文关键词:non-alcoholic fatty liver disease somato-type in Chinese medicine body mass index blood lipids hepato-enzymology

基金项目:国家“十一五”科技支撑计划项目(No.2007BAI20B095)

作者	单位
赵文霞	河南中医学院第一附属医院消化病诊疗中心
段荣章	河南中医学院
刘君颖	河南中医学院第一附属医院消化病诊疗中心

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中文摘要:

目的探讨非酒精性脂肪性肝病(NAFLD)体质类型分布特点及其与体重指数(BMI)、血脂及肝功能酶学等的关系。方法 2008年1—12月,对诊断为NAFLD的1163例患者进行中医体质分型,并观察其与体重指数、血脂及肝功能酶学的关系。结果 1163例NAFLD患者中,痰湿质371例,气虚质401例,占全部病例的66.38%。痰湿质患者的BMI、血脂(TC、TG、LDL-C)、肝功能酶学(ALT、AST、GGT)水平较其他体质类型患者均明显增高,差异有统计学意义(P<0.05)。结论痰湿质和气虚质是NAFLD发病的主要体质类型;痰湿质较其他体质类型更易出现体重指数异常、血脂异常及肝功能酶学异常。

英文摘要:

Objective To investigate the distribution of somato-types in Chinese medicine and its correlations with body mass index (BMI),blood lipids and hepato-enzymes in patients with non-alcoholic fatty liver disease (NAFLD).Methods From January 2008 to December 2008,the somato-types of 1 163 NAFLD patients were categorized,and its correlations with BMI,blood lipids and hepato-enzymes were analyzed.Results Among the 1 163 patients,401 were categorized as qi-deficiency type and 371 as phlegm-dampness type,accounting for 66.38%.Levels of BMI,blood lipids (TC,TG,LDL) and hepato-enzymes (ALT,AST,GGT) in patients of phlegm-dampness type were higher than those in patients of other types,the differences were statistically significant (P<0.05).Conclusions Qi-deficiency type and phlegm-dampness type are the dominant pathogenetic somsto-types in patients with NAFLD;abnormal BMI,blood lipids and hepato-enzymes may present in those of phlegm-dampness type more frequently.

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