| 张雪,武连仲,王海荣,樊小农.调神活血止痛针刺法与卡马西平治疗丘脑痛作用特点的动态变化观察[J].中国中西医结合杂志,2011,31(6):741-744 |
| 调神活血止痛针刺法与卡马西平治疗丘脑痛作用特点的动态变化观察 |
| Dynamic Observation on Therapeutic Features of Thalamic Pain by Mind Calming,Blood Activating and Pain Relief Acupuncture and Carbamazepine |
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| DOI： |
| 中文关键词: 丘脑痛 调神活血止痛针刺法 卡马西平 变化曲线 |
| 英文关键词:thalamic pain mind calming,blood activating and pain relief acupuncture Carbamazepine changing curve |
| 基金项目:天津中医药大学第一附属医院“拓新工程”基金资助项目(No.0804) |
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| 中文摘要: |
| 目的观察调神活血止痛针刺法与卡马西平治疗丘脑痛的作用特点。方法采用交叉试验设计,将11例确诊患者按最小不平衡指数法随机分为1组(先针刺治疗后西药治疗6例)和2组(先西药治疗后针刺治疗5例)。每种疗法疗程10天,两种方法间有10天洗脱期,总疗程30天。进行统计分析时,针刺组和西药组均为11例。分别应用视觉模拟评分法(VAS)和美国安德森肿瘤中心(Anderson Cancer Center)疼痛评估表(MD疼痛值)进行疗效评定,记录两组患者每天VAS和MD疼痛值,得到变化曲线。结果治疗后,两组患者VAS和MD疼痛值均较治疗前明显下降(P<0.05);在治疗期间,两组疼痛曲线均表现出下降的趋势,针刺组变化趋势是一个平缓而稳定的下降过程;西药组则显示先有较大幅度下降,在经过一个平台期后又出现了相对大幅度的下降,呈梯形样走势。结论累计效应可能是针刺主要的镇痛作用;西药可能更主要是通过迅速起效而发挥作用的。 |
| 英文摘要: |
| Objective To observe therapeutic features of thalamic pain by mind Calming,blood activating and pain relief acupuncture and Carbamazepine.Methods Crossover trial design was adopted. Eleven patients with confirmed diagnosis of thalamic pain were randomly assigned to two groups according to the minimal unbalance index method,i.e.,Group Ⅰ(Six patients received acupuncture first and then Western medicine.) and Group Ⅱ(Five patients received Western medicine first and then acupuncture).The therapeutic course for each group was ten days.There was a ten-day elution phase between the two therapeutic methods.The total therapeutic course was thirty days.Eleven patients were enrolled in the two groups for statistical analysis.The therapeutic efficacy was assessed with visual analogue scale(VAS) and the pain assessment scale of Anderson Cancer Center in the USA(MD Pain Evaluation value) respectively.The VAS and MD values of the two groups were recorded every day to get the dynamic curve.ResultsThe VAS and MD values obviously decreased in the two groups after treatment(P<0.05).The pain curves of the two groups showed a declining trend during the treatment.A gradual and stable descending process was shown in the acupuncture group.But a greater decrease first appeared in the Western medicine group,then a comparatively greater decrease occurred after one platform stage,showing ladder-shaped curve.Conclusions Cumulative potency may be the main analgesic effects of acupuncture.Western medicine may possibly play a role by rapid initiate effect. |
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