幽门螺杆菌和乳酸杆菌菌群失调与慢性胃病脾胃湿热证发病的关系

Relation between Dysbacteriosis of Helicobacter pylori and Lactobacillus acidophilus and the Pathogenesis of Chronic Gastropathy Patients of Pi-Wei Damp-heat Syndrome

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中文关键词: 幽门螺杆菌乳酸杆菌慢性胃病脾胃湿热证发病学

英文关键词:Helicobacter pylori Lactobacillus acidophilus chronic gastrosis Pi-Wei damp-heat syndrome pathogenesis

基金项目:国家自然科学基金资助项目(No.30772689);广东省自然科学基金资助项目(No.7004802)

作者	单位
劳绍贤	南方医科大学珠江医院
胡玲	南方医科大学珠江医院
程明	广州中医药大学脾胃研究所

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中文摘要:

"脾胃学说"是中医基础理论的重要组成部分,脾胃湿热证的发生是脾胃学说研究的重点内容,而舌苔为临床脾胃湿热证所体现的最主要体征之一。本文拟从微生态与发病学角度,初步提出胃黏膜和舌苔中幽门螺杆菌(Hp)与乳酸杆菌(LA)数量改变及其相互作用所引起的微生态失衡,可能与慢性胃病脾胃湿热证"邪正交争、阴阳失衡"之发病学特点有一定的相关性。

英文摘要:

Pi-Wei theory is an important component of the basic theory of Chinese medicine.The pathogenesis of Pi-Wei damp-heat syndrome is an important content of Pi-Wei theory.The tongue coating is one of the most important signs reflecting Pi-Wei damp-heat syndrome.From the perspective of microecology and pathogenesis,the microbial disequilibrium caused by quantity changes of Helicobacter pylori(Hp) and Lactobacillus acidophilus(LA) and their interaction in the gastric mucosa and the tongue coating might have certain correlation with "mutual struggle between the evil and the vital qi,the disequilibrium between yin and yang".The pathogenesis features of chronic gastrosis patients of Pi-Wei damp-heat syndrome was initially proposed in this article.

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