杜武勋,朱明丹,袁宏伟,冯利民,朱林平,刘岩,周营,魏聪聪,张少强.病证结合,方证相应的系统——系统的方证相应动态研究[J].中国中西医结合杂志,2012,32(6):839-842 |
病证结合,方证相应的系统——系统的方证相应动态研究 |
Dynamic Study of Correspondence of Prescription and Syndrome System:a System with Combination of Disease and Syndrome,Correspondence of Prescription and Syndrome |
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DOI: |
中文关键词: 病证结合 方证相应 代谢组学 整体系统 |
英文关键词:combination of disease and syndrome correspondence of prescription and syndrome metabolomics whole system |
基金项目:国家自然基金青年项目(No.8110512,No.81102534);国家自然基金面上项目(No.81173159) |
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中文摘要: |
通过目前证候物质基础与中药药效物质基础研究的现状与存在问题的分析,认为无论是"证"或"方"都是一个复杂的整体系统,研究方与证的物质基础,应在病证结合的基础上,遵循整体性原则、动态性原则。背离整体性原则,割裂方证的关联,无视动态的观念,可能将失去辨证论治与中医复方的特色和优势。代谢组学研究技术架起方与证研究的桥梁,寻找病与证和方与证的契合点及方与证效应的靶点,建立病证结合,方证相应的系统——系统的方证相应动态研究方法具有重要意义。 |
英文摘要: |
By analyzing the present situation and existing problems in the material bases of syndrome and Chinese materia medica,we think that either syndrome or prescription is a complex whole system.Studies of the material bases of syndrome and prescription should be established on the combination of disease and syndrome,following the holistic and dynamic principles.Departure from the holistic principle,separating the syndrome from the prescription,ignoring the dynamic concepts may possibly lose the features and advantages of syndrome typing and Chinese medicine preparations.The metabolomics research bridges the study of prescription and syndrome.It is of great significance in finding out the agreeable point of disease-syndrome-efficacy,establishing a dynamic research method with combination of disease and syndrome,correspondence of prescription and syndrome. |
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