826例高甘油三酯血症患者证候要素特征的隐结构模型评价

作者	单位	E-mail
何伟,郭树仁,刘平兰
谢雁鸣	中国中医科学院中医临床基础医学研究所（北京 100700）	zhinanb2012@yahoo.com.cn

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中文摘要:

目的评价高甘油三酯血症患者的主要中医证候要素特征。方法采用隐结构模型方法，构建826例高甘油三酯血症患者的隐树结构图，采用隐类概率、条件概率、互信息及累积信息覆盖率量化症状/证候数据，以人工判读方法诠释高甘油三酯血症患者的主要证候要素特征。结果以累积信息覆盖率达到95%为主要证候要素的判定标准，826例高甘油三酯血症患者以中、重度症状/证候表现为主（隐类概率分别为35%和60%），其证候要素以气虚、气滞、火热、瘀血、阴虚、阳虚为主，证候要素靶位以心、肝、肾为主。结论基于隐结构模型的证候要素评价方法，可量化各变量（证候要素、中医症状）的关联程度及发生概率。

英文摘要:

Objective To evaluate main Chinese medical syndrome elements and features of hypertriglyceridemia patients. Methods Using latent structure model （LSM） method， the latent structure diagram of 826 hypertriglyceridemia patients were established. Hypertriglyceridemia syndrome elements and features were interpreted by using latent probability，conditional probability，mutual information， and cumulative information coverage to quantify symptoms/syndromes data，as well as using manual interpretation methods. Results The accumulative information coverage rate reaching 95% was taken as the judgment standard for major syndrome elements. In the 826 hypertriglyceridemia patients， moderate and severe symptoms/syndromes （with the latent probability being 35% and 60% respectively） were dominant. The syndrome elements mainly included qi deficiency，qi stagnation，fire heat，stasis blood，yin deficiency，and yang deficiency. The main targets were dominated in Xin， Gan， and Shen. Conclusion LSM based syndrome element evaluation method could quantify the association degree of each variable （syndrome element； Chinese medical symptoms） and the occurrence probability.

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