艾滋病肺部感染聚类分析及证型分布特点初步研究

目的探讨艾滋病即获得性免疫缺陷综合征（acquired immunodeficiency syndrome，AIDS）肺部感染的中医证候特点。方法运用聚类分析方法，分析196例AIDS肺部感染患者的中医证型，并根据不同病情程度和CD4+数值分析各证型分布特点。结果中医基本证型归纳为风热外袭、痰热壅肺证61例（31.1%），肺脾两虚、痰湿阻肺证64例（32.7%），肺肾两亏、阴虚内热证71例（36.2%）3大类，3证型病情程度和CD4+的分布差异有统计学意义（P<0.05）。结论AIDS肺部感染病位涉及肺、脾、肾三脏；病邪涉及“风”、“热”、“痰”、“虚”，中医证型的分布与患者的免疫力情况有着密切联系。

英文摘要:

ObjectiveTo investigate Chinese medical features of acquired immunodeficiency syndrome （AIDS） patients with pulmonary infection. MethodsUsing cluster analysis method， Chinese medical syndromes of 196 AIDS patients with pulmonary infection were analyzed. The distribution features of each syndrome type were analyzed according to the severity and CD4+ numerical analysis. ResultsBasic Chinese medical syndrome types could be summed up as three kinds： exterior invasion of wind heat and phlegm heat obstructing Fei syndrome （61 cases， 31.1%）， Fei Pi deficiency and Fei stagnation of phlegm syndrome （64 cases， 32.7%）， Fei Shen deficiency and yin deficiency induced inner heat syndrome （71 cases， 36.2%）. There was statistical difference in the severity degree and the distribution of CD4+ among the three syndrome types （P<0.05）. ConclusionsAIDS patients with pulmonary infection involve Fei， Shen， and Pi. The pathogenic factors were related to "wind"， "heat"， "phlegm"， and "xu". The Chinese medical syndrome distribution was closely correlated with patients′ immunity.

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