冠心病的治疗性血管新生与活血化瘀

治疗性血管新生（therapeutic angiogenesis）是冠状动脉硬化性心脏病（coronary atherosclerotic heart disease，CAHD）治疗的新策略。而活血化瘀治法对于CAHD的基础研究和临床试验均有肯定疗效。用活血化瘀治法研究CAHD治疗性血管新生这一新的命题，可能会为CAHD的治疗提供更佳的治疗方案。笔者回顾活血化瘀药对CAHD治疗性血管新生的相关理论及新近研究，在病证结合的基础上从活血化瘀复方、单味药以及中药活性成分的基础实验和临床研究及其作用机制等角度探讨活血化瘀中药对CAHD治疗性血管新生现状与成就，为今后的研究提供一定的借鉴。

英文摘要:

Therapeutic angiogenesis comes into sight as a new strategy for coronary atherosclerotic heart disease （CAHD）. The therapeutic method of activating blood circulation to remove stasis has shown confirmative effect upon both fundamental researches and clinical trials of CAHD. Thus， the new proposition may provide a better treatment plan for CAHD to study on therapeutic angiogenesis with the therapeutic method of activating blood circulation to remove stasis. The author reviewed relevant theories and the latest researches， on the basis of combining diseases identification and syndrome typing， discussed the state quo and achievement of therapeutic angiogenesis in CAHD by Chinese herbal medicines （CHM） of activating blood circulation to remove stasis from fundamental and clinical researches and action mechanisms from standpoints of Chinese herbal compounds， single Chinese herb， effective herbal chemical composition， thus providing references for future researches.

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