新冠疫情下隔离人群焦虑情绪影响因素及针刺干预疗效观察

作者	单位
周夏芸;胡零三;周逸夫;李仲贤;阎路达;秦烨;周鹏	1.广州中医药大学第七临床医学院（深圳 518101）,2.深圳市宝安区中医院针灸科（深圳 518101）

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中文摘要:

目的调查新型冠状病毒感染（简称新冠）疫情下隔离人群的焦虑情绪，分析其相关因素，评价针刺干预急性焦虑状态隔离人群的临床疗效。方法于 2022年3月31日—9月9日对广州中医药大学附属宝安中医院分管隔离酒店的1 160位隔离人员进行问卷调查，采用自编一般资料调查表、焦虑自评量表（SAS）进行资料收集，并将符合急性焦虑标准且愿意进行临床干预研究的80例隔离人员随机分为疏肝调神针刺组（针刺组）、正念减压疗法组（正念组），每组40例，分别进行疏肝调神针刺、正念减压疗法干预，观察治疗前后的SAS评分、减分率及疗效。结果调查研究共回收问卷1 160份，剔除包含缺失值问卷4份，最终得到1 156 份有效问卷（99.7%），存在急性焦虑情绪的隔离人员共184 例，占比15.9%。单因素分析比较结果显示性别、受教育程度、密接史、睡眠状况是隔离人员出现急性焦虑状态的影响因素（P<0.05）。多因素Logistic回归分析（逐步向前法）结果显示，女性、高中以上学历、已婚、有密接史及睡眠变差是隔离人员出现焦虑症状的危险因素（P<0.05）。临床干预研究共纳入急性焦虑状态的隔离人员80例，针刺组及正念组各40例，均未出现脱落与剔除。与本组治疗前比较，两组治疗后SAS评分均下降（t针刺=15.562，t正念=11.571，P<0.001）。两组治疗后针刺组SAS评分差值d优于正念组（t=2.216，P<0.05）。与正念组同期比较，针刺组治疗后减分率（χ2=13.494，P<0.001）、疗效（χ2= 10.323， P<0.001）均优于正念组。结论女性、高中以上学历、已婚、有密接史及睡眠变差的隔离人员出现焦虑症状的可能性更大，疏肝调神针刺干预急性焦虑状态的疗效优于正念组。（中国临床试验注册中心注册，No. ChiCTR2200061291）。

英文摘要:

Objective To investigate the anxiety of isolated people under the epidemic of 2019-novel coronavirus infection，analyze its related factors，and evaluate the clinical efficacy of acupuncture intervention in isolated people with acute anxiety Methods From March 31，2022 to September 9，2022，a questionnaire survey was conducted on 1 160 isolated personnel in the isolation hotel of Bao 'an Hospital of Traditional Chinese Medicine affiliated to Guangzhou University of Traditional Chinese Medicine. The self-made general data questionnaire and self-rating anxiety scale （SAS） were used to collect data. Eighty isolated personnel who met the criteria of acute anxiety and were willing to carry out clinical intervention studies were randomly divided into Shugan Tiaoshen acupuncture group （acupuncture group） and mindfulness decompression therapy group （mindfulness group），with 40 cases in each group. The two groups received Shugan Tiaoshen acupuncture or mindfulness-based decompression therapy respectively，and the SAS score，reduction rate and efficacy before and after treatment were observed. Results A total of 1 160 questionnaires were collected in the survey，and 4 questionnaires with missing values were excluded. Finally，1 156 valid questionnaires （99.7%） were obtained，including 184 isolated people with acute anxiety，accounting for 15.9%. Univariate analysis showed that gender，education level，close contact history and sleep status were the influencing factors of acute anxiety in isolated personnel（P<0.05）. Multivariate logistic regression analysis（stepwise forward method）showed that female，high school education above，married，close contact history and poor sleep were risk factors for anxiety symptoms in isolated personnel （P<0.05）. A total of 80 patients with acute anxiety were included in the clinical intervention study，including 40 in the acupuncture group and 40 in the mindfulness group . Compared with the group before treatment，the SAS scores of the two groups decreased after treatment （t acupuncture= 15.562，t mindfulness = 11.571，P<0.001），and the difference of SAS scores between the two groups after treatment was statistically significant （t=2.216，P<0.05）. Compared with the mindfulness group at the same time，the reduction rate （chi2 = 13.494，P<0.001） and curative efficacy（chi2 =10.323，P<0.001）of the acupuncture group were significantly better than those of the mindfulness group. Conclusions Female，high school education above，married，with a close history and poor sleep isolation personnel are more likely to have symptoms of anxiety.The effect of Shugan Tiaoshen acupuncture on acute anxiety is better than that of the mindfulness group.（Chinese Clinical Trial Registry，No.ChiCTR2200061291）.

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