基于“血脉微癥”理论探讨动脉粥样硬化斑块防治思路

作者	单位
陈纪烨;李晓雅;张晓囡;王泽平;于宗良;李昕;刘龙涛	1.中国中医科学院西苑医院心血管病中心（北京 100091）,2.国家中医心血管病临床医学研究中心（北京 100091）,3.北京中医药大学研究生院（北京 100029）

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中文摘要:

动脉粥样硬化（AS）斑块是导致多种心脑血管不良事件发生发展的主要病理基础。中医药防治AS斑块疗效确切，但缺乏对AS斑块深入系统的中医学理论探讨。结合中西医学研究成果，课题组提出AS斑块“血脉微癥”理论，认为AS斑块以正虚为本，瘀毒为关键病理产物和致病因素，癥积内生为主要病理表征。临证可以“血脉微癥”理论为指导，以益气活血、解毒消癥为主治疗AS斑块。本文以中医学“瘀毒”理论为切入点，阐释“血脉微癥”理论内涵，以期为中医药防治AS斑块的研究提供理论依据和研究思路。

英文摘要:

Atherosclerosis（AS）plaque is the main pathological basis leading to the occurrence and development of various cardiovascular and cerebrovascular adverse events. Chinese medicine（CM）have definite curative effect on the prevention and treatment of AS plaque，but there is a lack of in-depth and systematic understanding of AS plaques based on CM theory. Based on the research results of CM and Western medicine， our research group put forward the theory of "micro Zheng in blood vessels" of AS plaque. According to the theory， AS plaque is based on qi deficiency， stasis and toxin are the key pathological products and pathogenic factors， and Zhengji is the main pathological characterization. In the clinical treatment of AS plaque， the theory of "micro Zheng in blood vessels" could be used as the guidance， and tonifying qi and promoting blood circulation， detoxification and eliminating Zheng could be taken as the basic principle. This article regards the theory of "stasis and toxin" in CM as the breakthrough point， and deeply explains the theoretical connotation of "micro Zheng in blood vessels"， in order to provide theoretical basis and research ideas for the research on the prevention and treatment of AS plaques by CM.

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